HitPredict

Interactor 1: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Interactor 2: ULK4 (Q96C45)
Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4)
Gene: ULK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Hs			1 1275
+	Dm
		661854 MIRO_DROME (2-616): 0: 722: 47.21		FUSED_DROME (1-279): 1.05e-24: 113: 29.23
+	Hs
		580880 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		MARK3_HUMAN (3-703): 5.72e-166: 514: 15.05
+	Hs
		692023 RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22		MARK3_HUMAN (3-703): 5.72e-166: 514: 15.05
+	Hs
		581132 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		MARK2_HUMAN (3-703): 4.2e-164: 511: 15.03
+	Hs
		953523 RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22		MARK2_HUMAN (3-703): 4.2e-164: 511: 15.03
+	Hs
		692024 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		MARK3_HUMAN (3-703): 5.72e-166: 514: 15.05
+	Hs
		955318 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		MARK2_HUMAN (3-703): 4.2e-164: 511: 15.03
+	Hs
		581026 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		ROCK1_HUMAN (2-754): 3.36e-132: 441: 15.22
+	Hs
		953428 RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22		ROCK1_HUMAN (2-754): 3.36e-132: 441: 15.22
+	Hs
		955133 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		ROCK1_HUMAN (2-754): 3.36e-132: 441: 15.22
+	Hs
		955482 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		MARK4_HUMAN (3-704): 3.05e-134: 430: 14.31
+	Hs
		581028 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		KCC2B_HUMAN (2-485): 1.18e-119: 389: 20.04
+	Hs
		354521 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		PAK4_HUMAN (1-283): 4.99e-25: 113: 29.37
+	Hs
		354617 RAC3_HUMAN (3-168): 9.64e-79: 249: 27.22		PAK4_HUMAN (1-283): 4.99e-25: 113: 29.37
+	Hs
		955705 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		PAK5_HUMAN (1-283): 5.33e-26: 117: 32.17
+	Hs
		354620 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		PAK4_HUMAN (1-283): 4.99e-25: 113: 29.37
+	Hs
		955638 CDC42_HUMAN (3-172): 5.7e-77: 244: 25.54		PAK6_HUMAN (7-279): 7.04e-25: 113: 29.35
+	Hs
		354702 RAB35_HUMAN (5-168): 3.57e-76: 242: 24.70		PAK4_HUMAN (1-283): 4.99e-25: 113: 29.37
+	Dm
		56118 CDC42_DROME (3-172): 4.04e-76: 242: 25.00		APKC_DROME (1-281): 1.74e-24: 112: 27.91
+	Dm
		828063 CDC42_DROME (3-172): 4.04e-76: 242: 25.00		PAKM_DROME (2-283): 4.47e-24: 110: 28.77