HitPredict

Interactor 1: DHRS4 (Q9BTZ2)
Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase) (CR) (NADPH-dependent retinol dehydrogenase/reductase) (NRDR) (humNRDR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (SCAD-SRL) (Short chain dehydrogenase/reductase family 25C member 2) (Protein SDR25C2) (Short-chain dehydrogenase/reductase family member 4)
Gene: DHRS4

Interactor 2: DHRS4 (Q9BTZ2)
Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase) (CR) (NADPH-dependent retinol dehydrogenase/reductase) (NRDR) (humNRDR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD) (SCAD-SRL) (Short chain dehydrogenase/reductase family 25C member 2) (Protein SDR25C2) (Short-chain dehydrogenase/reductase family member 4)
Gene: DHRS4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27499296
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains adh_short_C2~adh_short_C2
Common GO terms GO:0000253 - 3-keto sterol reductase activity
GO:0001758 - retinal dehydrogenase activity
GO:0004090 - carbonyl reductase (NADPH) activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
and 14 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 278
Hs

1 278
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+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024