HitPredict

Interactor 1: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Interactor 2: PHC2 (Q8IXK0)
Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2)
Gene: PHC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.733

The method score is based on:

Property Details
Experiments 27705803, 24981860, 15386022, 37014752, 40437099, 22325352
Identification Methods affinity chromatography technology, cross-linking study, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008270 - zinc ion binding
GO:0031519 - PcG protein complex
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 406
Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025