HitPredict

Interactor 1: ASPM (Q8IZT6)
Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog)
Gene: ASPM

Interactor 2: CNKR1 (Q969H4)
Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR 1) (CNK homolog protein 1) (CNK1) (hCNK1) (Connector enhancer of KSR-like)
Gene: CNKSR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3477 Hs			1 720
+	Hs
		1292783 ASPM_HUMAN (1-3477): 0: 2235: 100.00		SKAP1_HUMAN (398-546): 2.02e-21: 98.4: 22.22
+	Hs
		174744 SPTN2_HUMAN (929-3043): 1.07e-97: 357: 10.29		SPTB2_HUMAN (12-538): 2.48e-78: 276: 14.91
+	Hs
		1028869 SPTN4_HUMAN (921-3063): 3.06e-92: 339: 9.57		SPTB2_HUMAN (12-538): 2.48e-78: 276: 14.91
+	Rn
		1251028 ACTN1_RAT (937-1797): 3.09e-79: 285: 11.56		Q6XD99_RAT (12-538): 1.92e-80: 282: 15.13
+	Dm
		1028094 SPTCB_DROME (929-3098): 3.11e-89: 329: 9.29		Q9VZQ3_DROME (61-657): 6.91e-41: 164: 13.95
+	Hs
		555703 ACTN1_HUMAN (937-1797): 3.35e-79: 285: 11.56		PKHA7_HUMAN (321-714): 8.46e-41: 162: 15.19
+	Hs
		555757 ACTN1_HUMAN (937-1797): 3.35e-79: 285: 11.56		PKHA4_HUMAN (383-502): 1.22e-26: 118: 26.40
+	Hs
		1028918 MYO5A_HUMAN (1780-2618): 8.06e-28: 126: 10.43		SPTB2_HUMAN (12-538): 2.48e-78: 276: 14.91
+	Hs
		1028889 MYO5C_HUMAN (2658-3307): 6.48e-23: 110: 10.82		SPTB2_HUMAN (12-538): 2.48e-78: 276: 14.91
+	Hs
		555716 ACTN1_HUMAN (937-1797): 3.35e-79: 285: 11.56		RHG24_HUMAN (402-535): 1.86e-13: 76.1: 19.31
+	Hs
		1143271 PLEC_HUMAN (2048-3476): 2e-19: 99.4: 7.47		PKHA5_HUMAN (329-717): 2.1e-47: 183: 15.74
+	Mm
		547390 DMD_MOUSE (1405-3472): 2.1e-22: 109: 6.93		SNTG1_MOUSE (139-507): 6.69e-43: 164: 16.58
+	Hs
		1143289 PLEC_HUMAN (2048-3476): 2e-19: 99.4: 7.47		RHG23_HUMAN (132-661): 6.3e-42: 166: 10.57
+	Dm
		52562 A1Z6Z9_DROME (1331-1972): 6.14e-20: 100: 12.17		Q9VZQ3_DROME (61-657): 6.91e-41: 164: 13.95
+	Hs
		1434326 MYO5A_HUMAN (1780-2618): 8.06e-28: 126: 10.43		PKHA4_HUMAN (383-502): 1.22e-26: 118: 26.40
+	Hs
		547481 DMD_HUMAN (1492-3476): 2.11e-24: 115: 7.10		PKHA4_HUMAN (383-502): 1.22e-26: 118: 26.40
+	Hs
		1433978 MYO5C_HUMAN (2658-3307): 6.48e-23: 110: 10.82		PKHA4_HUMAN (383-502): 1.22e-26: 118: 26.40
+	Hs
		535950 MYH3_HUMAN (1826-3029): 7.18e-23: 110: 8.80		PKHA4_HUMAN (383-502): 1.22e-26: 118: 26.40
+	Hs
		1143267 PLEC_HUMAN (2048-3476): 2e-19: 99.4: 7.47		PKHA4_HUMAN (383-502): 1.22e-26: 118: 26.40
+	Hs
		1327353 MYO5C_HUMAN (2658-3307): 6.48e-23: 110: 10.82		AFAP1_HUMAN (379-494): 3.04e-09: 62.3: 19.17