HitPredict

Interactor 1: STK40 (Q8N2I9)
Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495)
Gene: STK40

Interactor 2: MTCL1 (Q9Y4B5)
Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2)
Gene: MTCL1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	28089446
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 435 Hs			1 1905
+	Hs
		1270564 MARK2_HUMAN (7-422): 4.84e-122: 374: 21.19		MTCL1_HUMAN (1-1905): 0: 835: 100.00
+	Hs
		1396685 MARK4_HUMAN (4-433): 5.45e-122: 373: 20.32		MTCL1_HUMAN (1-1905): 0: 835: 100.00
+	Hs
		692171 MARK3_HUMAN (3-433): 5.08e-121: 371: 19.55		MTCL1_HUMAN (1-1905): 0: 835: 100.00
+	Hs
		773251 MARK4_HUMAN (4-433): 5.45e-122: 373: 20.32		MYH10_HUMAN (115-930): 6.88e-23: 109: 10.92
+	Hs
		322841 MARK2_HUMAN (7-422): 4.84e-122: 374: 21.19		MTCL2_HUMAN (9-1158): 6.28e-18: 93.2: 12.77
+	Hs
		322858 MARK4_HUMAN (4-433): 5.45e-122: 373: 20.32		MTCL2_HUMAN (9-1158): 6.28e-18: 93.2: 12.77
+	Hs
		322803 MARK3_HUMAN (3-433): 5.08e-121: 371: 19.55		MTCL2_HUMAN (9-1158): 6.28e-18: 93.2: 12.77
+	Hs
		772961 MARK4_HUMAN (4-433): 5.45e-122: 373: 20.32		MYH9_HUMAN (1054-1551): 1.52e-15: 85.5: 10.67
+	Hs
		728066 AKT1_HUMAN (6-401): 1.19e-118: 356: 21.14		MYH9_HUMAN (1054-1551): 1.52e-15: 85.5: 10.67
+	Hs
		728275 AKT1_HUMAN (6-401): 1.19e-118: 356: 21.14		GRDN_HUMAN (309-722): 1.57e-14: 81.9: 20.40
+	Mm
		728520 AKT1_MOUSE (1-401): 2.55e-119: 358: 21.07		GRDN_MOUSE (338-1203): 4.6e-13: 77.3: 16.57
+	Mm
		1210031 AKT2_MOUSE (9-401): 6.83e-119: 356: 21.36		GRDN_MOUSE (338-1203): 4.6e-13: 77.3: 16.57
+	Hs
		587568 AKT1_HUMAN (6-401): 1.19e-118: 356: 21.14		DESP_HUMAN (294-843): 6.24e-12: 73.4: 16.70
+	Hs
		666238 KPCL_HUMAN (4-368): 4.71e-118: 361: 21.56		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15
+	Mm
		591040 KPCE_MOUSE (2-400): 5.38e-96: 305: 20.83		MYH6_MOUSE (149-699): 1.07e-14: 82.4: 12.05
+	Mm
		591067 KPCE_MOUSE (2-400): 5.38e-96: 305: 20.83		MYH7_MOUSE (171-770): 7.78e-14: 79.7: 10.00
+	Hs
		773254 TRIB3_HUMAN (161-325): 4.5e-25: 107: 38.10		MYH10_HUMAN (115-930): 6.88e-23: 109: 10.92
+	Rn
		108135 AAPK1_RAT (162-326): 1.01e-22: 102: 33.94		G3V6P7_RAT (152-923): 3.18e-23: 110: 10.51
+	Hs
		322823 AAPK1_HUMAN (162-326): 1.03e-22: 102: 33.94		MTCL2_HUMAN (9-1158): 6.28e-18: 93.2: 12.77
+	Hs
		772969 TRIB3_HUMAN (161-325): 4.5e-25: 107: 38.10		MYH9_HUMAN (1054-1551): 1.52e-15: 85.5: 10.67