Interactor 1: DOCK8 (Q8NF50)
Dedicator of cytokinesis protein 8
Gene: DOCK8
Interactor 2: DOCK8 (Q8NF50)
Dedicator of cytokinesis protein 8
Gene: DOCK8
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956 |
| Identification Methods | two hybrid, two hybrid array |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DHR-2_Lobe_A~DHR-2_Lobe_A, DHR-2_Lobe_A~DHR-2_Lobe_B, DHR-2_Lobe_B~DHR-2_Lobe_C, DHR-2_Lobe_C~DHR-2_Lobe_C, DOCK-C2~DOCK-C2 |
| Common GO terms | GO:0001771 - immunological synapse formation GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 14 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025