HitPredict

Interactor 1: PK1IP (Q9NWT1)
p21-activated protein kinase-interacting protein 1 (PAK/PLC-interacting protein 1) (hPIP1) (PAK1-interacting protein 1) (WD repeat-containing protein 84)
Gene: PAK1IP1

Interactor 2: RCC2 (Q9P258)
Protein RCC2 (RCC1-like protein TD-60) (Telophase disk protein of 60 kDa)
Gene: RCC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25074804
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 392 Hs			1 522
+	Hs
		903569 WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66		RCC2_HUMAN (1-522): 9.06e-179: 514: 100.00
+	Hs
		1288357 SNR40_HUMAN (237-391): 4.8e-13: 71.8: 9.62		RCC2_HUMAN (1-522): 9.06e-179: 514: 100.00
+	Mm
		1225124 FBXW7_MOUSE (1-146): 3.61e-26: 112: 19.48		NEK9_MOUSE (162-519): 1.6e-59: 213: 19.02
+	Hs
		319956 FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48		HERC2_HUMAN (214-511): 1.74e-56: 206: 21.17
+	Hs
		1065058 FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72		HERC3_HUMAN (407-513): 7.52e-16: 82.9: 18.10
+	Hs
		921597 GBB2_HUMAN (139-381): 1.14e-22: 99.5: 7.53		HERC4_HUMAN (275-510): 1.48e-51: 191: 25.00
+	Hs
		1355831 FBW1A_HUMAN (2-286): 6.86e-64: 216: 16.72		HERC5_HUMAN (193-479): 1.5e-09: 62.8: 22.19
+	Hs
		1065055 FBW1B_HUMAN (3-231): 7.86e-44: 161: 16.87		HERC3_HUMAN (407-513): 7.52e-16: 82.9: 18.10
+	Hs
		578408 WDR5_HUMAN (202-377): 2.11e-30: 120: 13.66		RCC1_HUMAN (311-517): 7.82e-27: 114: 18.39
+	Hs
		578413 GBB2_HUMAN (139-381): 1.14e-22: 99.5: 7.53		RCC1_HUMAN (311-517): 7.82e-27: 114: 18.39
+	Hs
		1281460 FBXW7_HUMAN (1-146): 6.23e-26: 111: 19.48		HERC5_HUMAN (193-479): 1.5e-09: 62.8: 22.19