HitPredict

Interactor 1: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23752268
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Dicer_dimer~Ribonuclease_3, Helicase_C~Helicase_C, Helicase_C~ResIII, PAZ~PAZ, PAZ~Ribonuclease_3, ResIII~ResIII, Ribonuclease_3~Ribonuclease_3
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding
GO:0004386 - helicase activity
and 32 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1922
Hs

1 1922
+ Mm
+ Hs
+ Hs
+ Ce
+ Ce
+ Ce
+ Hs
+ At
+ Mm
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024