Interactor 1: ICEF1 (Q8WWN9)
Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E)
Gene: IPCEF1
Interactor 2: CYH2 (Q99418)
Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)
Gene: CYTH2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.87 | 1.00 | 0.936 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12920129, 28514442, 32296183, 33961781, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation, validated two hybrid |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~PH, PH~Sec7 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
