HitPredict

Interactor 1: EED (Q921E6)
Polycomb protein EED
Gene: EED

Interactor 2: ARC1B (Q9WV32)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: Arpc1b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 441 Mm			1 372
+	Mm
		984361 EED_MOUSE (1-441): 1.63e-90: 283: 100.00		GBB2_MOUSE (128-366): 3.58e-38: 141: 13.53
+	Hs
		261437 TBL1X_HUMAN (25-441): 2.18e-71: 237: 11.74		TBL1Y_HUMAN (1-171): 2.39e-32: 128: 13.33
+	Hs
		179238 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		ARC1B_HUMAN (1-372): 3.48e-79: 249: 97.31
+	Dm
		1463899 WDS_DROME (181-441): 2.05e-48: 170: 15.21		WDS_DROME (1-233): 4.22e-56: 189: 13.87
+	Ca
		515422 TUP1_CANAL (4-263): 3e-56: 195: 14.50		TUP1_CANAL (141-362): 4.51e-39: 147: 12.93
+	Sc
		673545 NLE1_YEAST (4-263): 2.52e-49: 177: 14.05		NLE1_YEAST (129-367): 3.73e-40: 150: 11.81
+	Hs
		261352 TBL1X_HUMAN (25-441): 2.18e-71: 237: 11.74		TBL1X_HUMAN (7-83): 1.58e-13: 73.9: 20.78
+	Hs
		261440 TBL1X_HUMAN (25-441): 2.18e-71: 237: 11.74		TBL1R_HUMAN (1-83): 3.79e-13: 72.3: 18.82
+	Hs
		1410246 TBL1R_HUMAN (25-267): 1.29e-47: 172: 14.40		TBL1Y_HUMAN (1-171): 2.39e-32: 128: 13.33
+	Dm
		1463923 FBXW7_DROME (224-441): 2.91e-25: 111: 15.53		WDS_DROME (1-233): 4.22e-56: 189: 13.87
+	Hs
		1334151 POC1B_HUMAN (186-440): 3.47e-46: 167: 15.56		POC1A_HUMAN (1-123): 5.74e-30: 120: 14.63
+	Hs
		1380064 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		FBXW7_HUMAN (124-365): 6.17e-46: 168: 12.65
+	Hs
		965141 FBXW7_HUMAN (219-439): 2.95e-26: 113: 15.32		WDR5_HUMAN (173-365): 1.09e-45: 160: 14.87
+	Hs
		965276 NLE1_HUMAN (296-440): 9.08e-25: 108: 16.45		WDR5_HUMAN (173-365): 1.09e-45: 160: 14.87
+	Hs
		965151 SNR40_HUMAN (298-441): 2.31e-21: 96.6: 14.29		WDR5_HUMAN (173-365): 1.09e-45: 160: 14.87
+	Hs
		984306 NLE1_HUMAN (296-440): 9.08e-25: 108: 16.45		GBB2_HUMAN (128-366): 3.58e-38: 141: 13.53
+	Sc
		922098 COPA_YEAST (9-295): 5.36e-29: 122: 11.15		COPA_YEAST (193-364): 1.57e-25: 110: 14.37
+	Hs
		1450936 NLE1_HUMAN (296-440): 9.08e-25: 108: 16.45		NLE1_HUMAN (276-369): 2.17e-15: 79.3: 13.54