Interactor 1: DRICE (O01382)
Caspase (EC 3.4.22.-) (drICE) [Cleaved into: Caspase subunit p21; Caspase subunit p12]
Gene: DRICE

Interactor 2: CASP1 (O02002)
Caspase-1 (EC 3.4.22.-) [Cleaved into: Caspase-1 subunit p22; Caspase-1 subunit p13]
Gene: Dcp-1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.820

The method score is based on:

Property Details
Experiments 24862573, 28806103, unassigned4
Identification Methods enzymatic study, experimental interaction detection
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C14~Peptidase_C14
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0006915 - apoptotic process
GO:0010623 - programmed cell death involved in cell development
and 8 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 339
Dm

1 323
+ Dm
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+ Mm
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Last updated: 15 Jul 2024