HitPredict

Interactor 1: SEPT8 (Q92599)
Septin-8
Gene: SEPTIN8

Interactor 2: BORG4 (Q9H3Q1)
Cdc42 effector protein 4 (Binder of Rho GTPases 4)
Gene: CDC42EP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015630 - microtubule cytoskeleton
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 356
+	Hs
		1432839 SEP10_HUMAN (1-429): 0: 586: 72.96		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1121197 SEPT6_HUMAN (1-429): 0: 580: 76.22		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1256422 SEP14_HUMAN (10-423): 0: 549: 63.77		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1156417 SEPT7_HUMAN (2-427): 0: 547: 40.83		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1432837 SEP11_HUMAN (11-402): 0: 546: 81.12		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		210505 SEPT4_HUMAN (2-382): 1.87e-174: 500: 36.67		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1406706 SEPT5_HUMAN (1-383): 8.98e-172: 489: 36.99		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1137009 SEPT2_HUMAN (9-353): 1.01e-162: 466: 38.98		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1432842 SEPT9_HUMAN (8-319): 8.09e-157: 459: 39.81		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1432841 SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40		BORG4_HUMAN (1-356): 3.61e-128: 373: 100.00
+	Hs
		1025857 SEP10_HUMAN (1-429): 0: 586: 72.96		BORG5_HUMAN (3-227): 4.11e-53: 181: 32.16
+	Hs
		1121206 SEPT6_HUMAN (1-429): 0: 580: 76.22		BORG2_HUMAN (2-229): 1.36e-56: 186: 24.21
+	Hs
		158725 SEPT6_HUMAN (1-429): 0: 580: 76.22		BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86
+	Hs
		1156434 SEPT7_HUMAN (2-427): 0: 547: 40.83		BORG2_HUMAN (2-229): 1.36e-56: 186: 24.21
+	Hs
		158727 SEPT7_HUMAN (2-427): 0: 547: 40.83		BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86