HitPredict

Interactor 1: OSTF1 (Q92882)
Osteoclast-stimulating factor 1
Gene: OSTF1

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C2~SH3_1
Common GO terms	GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 214 Hs			1 1343
+	Hs
		1366022 ANS1A_HUMAN (40-213): 2.11e-36: 136: 17.42		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1030677 ANK2_HUMAN (47-213): 2.04e-35: 134: 17.07		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		104601 ANK2_MOUSE (47-213): 2.04e-35: 134: 17.07		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		1400164 RAI14_HUMAN (3-209): 2.6e-34: 130: 19.23		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		592953 ANK1_HUMAN (47-213): 4.67e-31: 121: 16.24		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1400179 KDIS_HUMAN (2-205): 2.15e-25: 105: 16.83		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1400144 TANC2_HUMAN (10-195): 1.35e-21: 94.2: 19.17		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		59038 TANC2_MOUSE (10-195): 1.44e-21: 94.2: 18.65		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Mm
		104588 ANS1B_MOUSE (1-110): 1.09e-09: 59.5: 17.27		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		1219085 ANS1A_HUMAN (40-213): 2.11e-36: 136: 17.42		DAB2P_HUMAN (97-1342): 0: 778: 46.78
+	Hs
		1219083 ANS1B_HUMAN (1-110): 1.17e-09: 59.5: 17.27		DAB2P_HUMAN (97-1342): 0: 778: 46.78
+	Hs
		1279998 ANS1B_HUMAN (1-110): 1.17e-09: 59.5: 17.27		NGAP_HUMAN (84-1341): 0: 731: 42.62
+	Hs
		862880 ANR11_HUMAN (51-194): 1.69e-36: 137: 30.56		IQGA1_HUMAN (219-857): 5.22e-123: 421: 13.35
+	Hs
		863008 RAI14_HUMAN (3-209): 2.6e-34: 130: 19.23		IQGA1_HUMAN (219-857): 5.22e-123: 421: 13.35
+	Hs
		1091391 ANK3_HUMAN (8-213): 2.39e-34: 131: 13.98		IQGA2_HUMAN (216-848): 1.23e-121: 416: 14.05
+	Hs
		943981 RIPK4_HUMAN (51-213): 2.39e-17: 81.9: 19.63		IQGA3_HUMAN (214-824): 5.28e-119: 409: 12.04
+	Hs
		1290486 Q9H4D1_HUMAN (51-213): 3.46e-17: 81.2: 19.63		IQGA3_HUMAN (214-824): 5.28e-119: 409: 12.04
+	Hs
		635706 GRB2_HUMAN (11-66): 5.91e-12: 64.3: 48.21		RASA1_HUMAN (184-715): 1.23e-128: 425: 23.32
+	Hs
		862791 GRB2_HUMAN (11-66): 5.91e-12: 64.3: 48.21		IQGA1_HUMAN (219-857): 5.22e-123: 421: 13.35
+	Hs
		637956 TANC2_HUMAN (10-195): 1.35e-21: 94.2: 19.17		NF1_HUMAN (408-712): 3.22e-82: 301: 23.21