HitPredict

Interactor 1: STK25 (O00506)
Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)
Gene: STK25

Interactor 2: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 426 Hs			1 307
+	Hs
		138821 STK25_HUMAN (1-426): 3.97e-155: 446: 100.00		PP2AB_HUMAN (6-307): 0: 525: 65.23
+	Hs
		138824 STK25_HUMAN (1-426): 3.97e-155: 446: 100.00		PP2AA_HUMAN (6-307): 0: 524: 65.89
+	Hs
		977624 STK24_HUMAN (13-424): 2.35e-140: 409: 71.98		PP2AB_HUMAN (6-307): 0: 525: 65.23
+	Hs
		994437 STK24_HUMAN (13-424): 2.35e-140: 409: 71.98		PP2AA_HUMAN (6-307): 0: 524: 65.89
+	Hs
		76368 B4DR80_HUMAN (10-416): 3.1e-139: 406: 68.46		PP2AB_HUMAN (6-307): 0: 525: 65.23
+	Hs
		76369 B4DR80_HUMAN (10-416): 3.1e-139: 406: 68.46		PP2AA_HUMAN (6-307): 0: 524: 65.89
+	Hs
		977602 STK26_HUMAN (15-420): 1.17e-135: 397: 67.32		PP2AB_HUMAN (6-307): 0: 525: 65.23
+	Hs
		994404 STK26_HUMAN (15-420): 1.17e-135: 397: 67.32		PP2AA_HUMAN (6-307): 0: 524: 65.89
+	Dm
		661944 AKT1_DROME (18-330): 1.35e-130: 391: 26.17		PP2A_DROME (2-307): 0: 524: 64.05
+	Hs
		994423 AKT3_HUMAN (2-344): 2.71e-132: 390: 23.36		PP2AA_HUMAN (6-307): 0: 524: 65.89
+	Dm
		661970 Q9VEN3_DROME (12-361): 1.1e-129: 389: 68.09		PP2A_DROME (2-307): 0: 524: 64.05
+	Dm
		661923 KCC2A_DROME (7-426): 1.18e-130: 388: 19.30		PP2A_DROME (2-307): 0: 524: 64.05
+	Hs
		728574 AKT2_HUMAN (19-303): 9.31e-131: 386: 27.30		PP2AA_HUMAN (6-307): 0: 524: 65.89
+	Mm
		728515 AKT1_MOUSE (6-303): 8.09e-130: 384: 27.36		PP2AA_MOUSE (6-307): 0: 524: 65.89
+	Ce
		113985 GCK1_CAEEL (12-363): 1.14e-125: 379: 65.16		PP2A_CAEEL (2-307): 0: 524: 63.73
+	Mm
		728514 AKT1_MOUSE (6-303): 8.09e-130: 384: 27.36		PP1A_MOUSE (2-304): 0: 518: 44.20
+	Hs
		651638 KAPCB_HUMAN (4-315): 9.01e-131: 382: 23.75		PP1A_HUMAN (2-304): 0: 517: 43.89
+	Hs
		994288 M4K3_HUMAN (12-355): 2.72e-118: 367: 42.78		PP2AA_HUMAN (6-307): 0: 524: 65.89
+	Dm
		661952 HIPPO_DROME (3-385): 8.05e-120: 365: 39.79		PP2A_DROME (2-307): 0: 524: 64.05
+	Hs
		967698 PAK1_HUMAN (15-295): 1.69e-120: 362: 44.52		PP1A_HUMAN (2-304): 0: 517: 43.89