Interactor 1: BCL9 (O00512)
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)
Gene: BCL9
Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.926 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24360964, 31073027, 34079125, 17052462, 11955446 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, isothermal titration calorimetry, x-ray crystallography, pull down, two hybrid |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arm~BCL9 |
| Common GO terms | GO:0003713 - transcription coactivator activity GO:0005654 - nucleoplasm GO:0006366 - transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0060070 - canonical Wnt signaling pathway and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
