Interactor 1: M3K4 (O08648)
Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)
Gene: Map3k4

Interactor 2: GSK3B (Q9WV60)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 17726008
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0016310 - phosphorylation
GO:0035556 - intracellular signal transduction
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1597
Mm

1 420
+ Hs
+ Hs
+ Hs
+ Dm
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+ Dm
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+ At
+ Hs
+ At
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+ At

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Last updated: 15 Jul 2024