Interactor 1: DLL1 (O00548)
Delta-like protein 1 (Drosophila Delta homolog 1) (Delta1) (H-Delta-1)
Gene: DLL1
Interactor 2: NOTC3 (Q9UM47)
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Gene: NOTCH3
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11006133 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DSL~EGF_CA, EGF~EGF, EGF~EGF_CA, EGF~hEGF, DL-JAG_EGF-like~EGF, EGF_CA~MNNL, MNNL~hEGF |
| Common GO terms | GO:0005509 - calcium ion binding GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0007219 - Notch signaling pathway GO:0045665 - negative regulation of neuron differentiation and 1 others more... |
| Homologous interactions | 14 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
