HitPredict

Interactor 1: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36950384
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0014069 - postsynaptic density
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1343 Hs			1 1128
+	Mm
		104620 SYGP1_MOUSE (1-1343): 0: 1003: 98.88		DLG2_MOUSE (1011-1128): 3.03e-16: 86.2: 17.60
+	Hs
		1006093 SYGP1_HUMAN (1-1343): 0: 1004: 100.00		DLG4_HUMAN (1011-1125): 1.86e-15: 83.5: 23.58
+	Mm
		104543 SYGP1_MOUSE (1-1343): 0: 1003: 98.88		DLG4_MOUSE (1011-1125): 1.81e-15: 83.5: 23.58
+	Mm
		104585 SYGP1_MOUSE (1-1343): 0: 1003: 98.88		DLG1_MOUSE (954-1095): 6.84e-14: 78.5: 16.08
+	Mm
		104504 SYGP1_MOUSE (1-1343): 0: 1003: 98.88		DLG3_MOUSE (866-1094): 1.6e-13: 77.3: 14.35
+	Hs
		1325754 SYGP1_HUMAN (1-1343): 0: 1004: 100.00		LNX2_HUMAN (889-1127): 2.68e-13: 76.2: 13.47
+	Hs
		1368714 SYGP1_HUMAN (1-1343): 0: 1004: 100.00		DLG3_HUMAN (874-1094): 9.36e-13: 74.7: 16.67
+	Hs
		1348443 SYGP1_HUMAN (1-1343): 0: 1004: 100.00		LNX1_HUMAN (861-1125): 9.54e-13: 74.5: 13.70
+	Hs
		1400153 SYGP1_HUMAN (1-1343): 0: 1004: 100.00		LIN7C_HUMAN (149-246): 1.59e-09: 60.8: 35.71
+	Rn
		723903 SYGP1_RAT (1-1302): 0: 976: 98.77		DLG4_RAT (1011-1125): 1.77e-15: 83.5: 23.58
+	Rn
		1224329 SYGP1_RAT (1-1302): 0: 976: 98.77		DLG3_RAT (866-1094): 1.75e-13: 77.3: 14.35
+	Hs
		1401133 NGAP_HUMAN (84-1341): 0: 731: 42.62		MAGI1_HUMAN (225-1124): 1.07e-39: 162: 13.15
+	Mm
		1190099 DAB2P_MOUSE (97-1342): 0: 781: 47.23		DLG4_MOUSE (1011-1125): 1.81e-15: 83.5: 23.58
+	Hs
		862948 IQGA1_HUMAN (219-857): 5.22e-123: 421: 13.35		MAGI1_HUMAN (225-1124): 1.07e-39: 162: 13.15
+	Hs
		863019 IQGA1_HUMAN (219-857): 5.22e-123: 421: 13.35		ZO2_HUMAN (38-374): 1.81e-23: 109: 15.27
+	Mm
		1190773 IQGA2_MOUSE (216-848): 2.64e-120: 412: 13.94		DLG4_MOUSE (1011-1125): 1.81e-15: 83.5: 23.58
+	Hs
		862915 IQGA1_HUMAN (219-857): 5.22e-123: 421: 13.35		LNX1_HUMAN (861-1125): 9.54e-13: 74.5: 13.70
+	Mm
		1223783 RASL1_MOUSE (162-680): 8.32e-119: 392: 19.93		DLG4_MOUSE (1011-1125): 1.81e-15: 83.5: 23.58
+	Hs
		637941 NF1_HUMAN (408-712): 3.22e-82: 301: 23.21		MAGI1_HUMAN (225-1124): 1.07e-39: 162: 13.15
+	Hs
		637890 NF1_HUMAN (408-712): 3.22e-82: 301: 23.21		PTN13_HUMAN (231-1015): 3.12e-22: 106: 11.51