HitPredict

Interactor 1: TCPQM (Q96SF2)
T-complex protein 1 subunit theta-like 2 (Chaperonin containing T-complex polypeptide 1 subunit 8-like 2)
Gene: CCT8L2

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 1298
+	Hs
		899218 TCPQ_HUMAN (1-532): 0: 535: 31.24		AMRA1_HUMAN (1-1298): 0: 1596: 100.00
+	Hs
		965190 TCPH_HUMAN (21-534): 0: 544: 20.83		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Cr
		68531 A8J7J2_CHLRE (20-522): 0: 582: 22.67		MUT11_CHLRE (7-304): 1.34e-70: 243: 15.50
+	Hs
		898980 TCPQ_HUMAN (1-532): 0: 535: 31.24		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		881861 TCPG_HUMAN (24-540): 0: 530: 22.89		WDR5_HUMAN (3-297): 1.09e-86: 287: 18.39
+	Hs
		1395137 TCPH_HUMAN (21-534): 0: 544: 20.83		DCAF5_HUMAN (13-774): 1.19e-70: 258: 14.37
+	Hs
		899176 TCPQ_HUMAN (1-532): 0: 535: 31.24		DCAF5_HUMAN (13-774): 1.19e-70: 258: 14.37
+	Hs
		1291941 TCPH_HUMAN (21-534): 0: 544: 20.83		WDR5B_HUMAN (4-207): 3.21e-55: 197: 14.68
+	Hs
		899171 TCPQ_HUMAN (1-532): 0: 535: 31.24		SNR40_HUMAN (45-334): 1.8e-54: 196: 12.04
+	Hs
		882014 TCPG_HUMAN (24-540): 0: 530: 22.89		WDR5B_HUMAN (4-207): 3.21e-55: 197: 14.68
+	Hs
		1334162 TCPH_HUMAN (21-534): 0: 544: 20.83		POC1A_HUMAN (83-434): 1.48e-41: 160: 12.30
+	Hs
		899135 TCPQ_HUMAN (1-532): 0: 535: 31.24		POC1A_HUMAN (83-434): 1.48e-41: 160: 12.30
+	Hs
		882038 TCPG_HUMAN (24-540): 0: 530: 22.89		POC1A_HUMAN (83-434): 1.48e-41: 160: 12.30
+	Sc
		793940 TCPH_YEAST (12-547): 0: 541: 20.40		TAF5_YEAST (9-127): 1.1e-32: 139: 22.22
+	Hs
		845257 TCPG_HUMAN (24-540): 0: 530: 22.89		LIS1_HUMAN (123-363): 2.02e-35: 142: 12.30
+	Hs
		161740 TCPQM_HUMAN (1-557): 0: 582: 100.00		APAF_HUMAN (33-203): 4.66e-16: 86.3: 19.23
+	Hs
		261435 TCPQM_HUMAN (1-557): 0: 582: 100.00		TBL1X_HUMAN (28-159): 4.55e-15: 82.1: 20.14
+	Hs
		1402707 TCPQM_HUMAN (1-557): 0: 582: 100.00		TBL1R_HUMAN (28-201): 1.6e-14: 80.1: 17.98
+	Hs
		1407542 TCPH_HUMAN (21-534): 0: 544: 20.83		KTNB1_HUMAN (167-610): 4.74e-17: 88.7: 8.64
+	Hs
		1407533 TCPH_HUMAN (21-534): 0: 544: 20.83		TBL1Y_HUMAN (5-169): 1.79e-13: 76.7: 21.67