HitPredict

Interactor 1: BHE41 (Q99PV5)
Class E basic helix-loop-helix protein 41 (bHLHe41) (Class B basic helix-loop-helix protein 3) (bHLHb3) (Differentially expressed in chondrocytes protein 2) (mDEC2)
Gene: Bhlhe41

Interactor 2: BHE41 (Q99PV5)
Class E basic helix-loop-helix protein 41 (bHLHe41) (Class B basic helix-loop-helix protein 3) (bHLHb3) (Differentially expressed in chondrocytes protein 2) (mDEC2)
Gene: Bhlhe41

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 23555304
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hairy_orange~Hairy_orange, HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003714 - transcription corepressor activity
and 14 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 410
Mm

1 410
+ Hs
+ Mm
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+ Hs
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+ Hs
+ Dm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Dm
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+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025