HitPredict

Interactor 1: RPAP3 (Q9H6T3)
RNA polymerase II-associated protein 3
Gene: RPAP3

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TPR_1~TPR_16, TPR_16~TPR_16, TPR_16~TPR_8
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 665 Hs			1 365
+	Hs
		1435166 RPAP3_HUMAN (1-665): 3.72e-124: 385: 100.00		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	At
		102835 SRFR1_ARATH (2-556): 8.42e-40: 159: 14.00		SGT1B_ARATH (11-365): 1.45e-72: 231: 34.08
+	At
		102834 SRFR1_ARATH (2-556): 8.42e-40: 159: 14.00		SGT1A_ARATH (33-365): 8.78e-72: 229: 34.52
+	Hs
		185549 OGT1_HUMAN (128-575): 8.34e-47: 180: 14.16		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Dm
		1478365 Q9VPN5_DROME (2-272): 2.1e-30: 127: 21.82		Q9VJD4_DROME (9-226): 1.39e-47: 165: 17.73
+	Hs
		718525 CDC27_HUMAN (118-517): 3.17e-32: 135: 13.15		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Dm
		1475708 Q9VPN5_DROME (2-272): 2.1e-30: 127: 21.82		Q9VH81_DROME (4-218): 1.06e-39: 149: 13.58
+	Hs
		185255 OGT1_HUMAN (128-575): 8.34e-47: 180: 14.16		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Pf
		86876 HSOP_PLAF7 (129-599): 8.88e-21: 98.6: 13.23		C0H586_PLAF7 (172-353): 2.01e-48: 163: 30.60
+	Hs
		185306 OGT1_HUMAN (128-575): 8.34e-47: 180: 14.16		TOM70_HUMAN (5-278): 4.48e-12: 69.1: 10.07
+	Hs
		226714 STIP1_HUMAN (96-594): 1.06e-18: 92: 14.13		SGTA_HUMAN (6-171): 3.2e-40: 146: 20.96
+	Hs
		731115 STIP1_HUMAN (96-594): 1.06e-18: 92: 14.13		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Hs
		226852 SGTB_HUMAN (286-399): 3.46e-16: 81.6: 41.23		SGTA_HUMAN (6-171): 3.2e-40: 146: 20.96
+	Hs
		731618 STIP1_HUMAN (96-594): 1.06e-18: 92: 14.13		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	At
		1379655 SPY_ARATH (271-623): 6.2e-17: 87: 9.65		SPY_ARATH (2-298): 4.09e-25: 108: 11.45
+	Hs
		185466 STIP1_HUMAN (96-594): 1.06e-18: 92: 14.13		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		185261 KDM6A_HUMAN (31-310): 1.84e-17: 89: 10.80		OGT1_HUMAN (51-342): 8.9e-18: 86.8: 9.12
+	Hs
		318038 TOM70_HUMAN (36-379): 1.3e-15: 82.6: 16.52		TTC28_HUMAN (7-112): 2.85e-13: 73.3: 26.36
+	Hs
		1389486 SGTB_HUMAN (286-399): 3.46e-16: 81.6: 41.23		SGTB_HUMAN (91-296): 3.67e-10: 62.2: 11.17