HitPredict

Interactor 1: GBB4 (Q9HAV0)
Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)
Gene: GNB4

Interactor 2: NR2E1 (Q9Y466)
Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (hTll)
Gene: NR2E1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Hs			1 385
+	Hs
		395850 GBB2_HUMAN (1-340): 8.23e-110: 325: 90.00		ESR1_HUMAN (8-385): 6.12e-98: 305: 29.06
+	Hs
		396978 GBB4_HUMAN (1-340): 1.1e-109: 324: 100.00		ESR1_HUMAN (8-385): 6.12e-98: 305: 29.06
+	Hs
		395848 GBB1_HUMAN (1-340): 6.08e-106: 315: 90.88		ESR1_HUMAN (8-385): 6.12e-98: 305: 29.06
+	Hs
		343250 GBB2_HUMAN (1-340): 8.23e-110: 325: 90.00		ERR2_HUMAN (11-383): 7.08e-92: 284: 28.95
+	Hs
		343280 GBB4_HUMAN (1-340): 1.1e-109: 324: 100.00		ERR2_HUMAN (11-383): 7.08e-92: 284: 28.95
+	Hs
		343249 GBB1_HUMAN (1-340): 6.08e-106: 315: 90.88		ERR2_HUMAN (11-383): 7.08e-92: 284: 28.95
+	Hs
		343219 GBB3_HUMAN (1-340): 3.74e-105: 313: 79.71		ERR2_HUMAN (11-383): 7.08e-92: 284: 28.95
+	Hs
		984224 GBB2_HUMAN (1-340): 8.23e-110: 325: 90.00		ESR2_HUMAN (2-382): 4.93e-86: 272: 26.75
+	Hs
		983545 GBB1_HUMAN (1-340): 6.08e-106: 315: 90.88		ESR2_HUMAN (2-382): 4.93e-86: 272: 26.75
+	Hs
		597366 GBB3_HUMAN (1-340): 3.74e-105: 313: 79.71		ESR2_HUMAN (2-382): 4.93e-86: 272: 26.75
+	Hs
		396440 WDR5B_HUMAN (3-211): 1.63e-57: 190: 20.91		ESR1_HUMAN (8-385): 6.12e-98: 305: 29.06
+	Hs
		520619 SNR40_HUMAN (130-340): 7.04e-58: 192: 24.77		RARA_HUMAN (14-384): 1.48e-89: 279: 25.34
+	Hs
		1367405 NLE1_HUMAN (2-124): 3.1e-32: 127: 25.20		ESR2_HUMAN (2-382): 4.93e-86: 272: 26.75
+	Hs
		395811 WDR5_HUMAN (263-340): 6.4e-19: 87.8: 23.08		ESR1_HUMAN (8-385): 6.12e-98: 305: 29.06
+	Hs
		833911 WDR5_HUMAN (263-340): 6.4e-19: 87.8: 23.08		HNF4A_HUMAN (2-383): 6.34e-98: 301: 30.16
+	Hs
		965376 WDR5_HUMAN (263-340): 6.4e-19: 87.8: 23.08		NR2E3_HUMAN (8-382): 2.31e-96: 295: 42.78
+	Hs
		209183 PRP4_HUMAN (51-253): 3.66e-11: 65.9: 24.88		ESR1_HUMAN (8-385): 6.12e-98: 305: 29.06
+	Mm
		965390 WDR5_MOUSE (263-340): 6.4e-19: 87.8: 23.08		ERR2_MOUSE (11-383): 4.32e-90: 279: 28.95
+	Hs
		965126 WDR5_HUMAN (263-340): 6.4e-19: 87.8: 23.08		ESR2_HUMAN (2-382): 4.93e-86: 272: 26.75
+	Hs
		163640 GNB5_HUMAN (129-340): 3.22e-42: 152: 22.62		NR6A1_HUMAN (16-375): 2.6e-33: 131: 25.82