HitPredict

Interactor 1: Q9NHP2 (Q9NHP2)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Gene: POSH

Interactor 2: Q9VB05 (Q9VB05)
ALG-2 interacting protein X (LD25543p)
Gene: ALiX

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	16698022
Identification Methods	pull down, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046330 - positive regulation of JNK cascade
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 838 Dm			1 836
+	Dm
		1266420 Q7K4D1_DROME (1-838): 1.24e-137: 431: 99.76		Q9VB05_DROME (1-836): 0: 573: 100.00
+	Hs
		1356984 SH3G1_HUMAN (70-197): 1.69e-36: 143: 29.86		PDC6I_HUMAN (1-831): 1.7e-177: 535: 40.50
+	Hs
		1154143 ITSN1_HUMAN (35-486): 4.41e-31: 133: 12.69		PDC6I_HUMAN (1-831): 1.7e-177: 535: 40.50
+	Mm
		1224159 SH3G1_MOUSE (82-197): 6.25e-38: 147: 31.06		PDC6I_MOUSE (1-831): 2.19e-166: 506: 40.57
+	Hs
		1280035 SH3R1_HUMAN (366-836): 8.24e-23: 106: 14.65		PDC6I_HUMAN (1-831): 1.7e-177: 535: 40.50
+	Hs
		1356985 SH3G2_HUMAN (193-254): 7.97e-16: 81.9: 38.71		PDC6I_HUMAN (1-831): 1.7e-177: 535: 40.50
+	Hs
		987797 GRB2_HUMAN (419-481): 1.63e-16: 81.5: 33.33		PDC6I_HUMAN (1-831): 1.7e-177: 535: 40.50
+	Hs
		1356968 STAM1_HUMAN (751-837): 1.91e-14: 79.2: 22.99		PDC6I_HUMAN (1-831): 1.7e-177: 535: 40.50
+	Hs
		1357030 CD2AP_HUMAN (677-833): 1.13e-13: 76.8: 14.47		PDC6I_HUMAN (1-831): 1.7e-177: 535: 40.50
+	Mm
		1224167 SH3G2_MOUSE (193-254): 5.33e-16: 82.3: 38.71		PDC6I_MOUSE (1-831): 2.19e-166: 506: 40.57
+	Mm
		1221266 GRB2_MOUSE (416-481): 1.37e-16: 81.5: 31.82		PDC6I_MOUSE (1-831): 2.19e-166: 506: 40.57
+	Hs
		1154169 ITSN1_HUMAN (35-486): 4.41e-31: 133: 12.69		PTN23_HUMAN (3-833): 7.42e-124: 410: 22.17
+	Hs
		292868 GRAP2_HUMAN (765-836): 1.58e-16: 83.8: 25.00		PTN23_HUMAN (3-833): 7.42e-124: 410: 22.17
+	Hs
		1408393 SH3G2_HUMAN (193-254): 7.97e-16: 81.9: 38.71		PTN23_HUMAN (3-833): 7.42e-124: 410: 22.17
+	Hs
		987935 GRB2_HUMAN (419-481): 1.63e-16: 81.5: 33.33		PTN23_HUMAN (3-833): 7.42e-124: 410: 22.17
+	Hs
		1368300 STAM1_HUMAN (751-837): 1.91e-14: 79.2: 22.99		PTN23_HUMAN (3-833): 7.42e-124: 410: 22.17
+	Hs
		1045040 SH3G1_HUMAN (70-197): 1.69e-36: 143: 29.86		PRB3_HUMAN (702-834): 7.61e-14: 75.7: 18.38
+	Hs
		1148610 SH3R1_HUMAN (366-836): 8.24e-23: 106: 14.65		SF3A2_HUMAN (710-832): 4.5e-14: 77.6: 13.82
+	Hs
		987659 GRB2_HUMAN (419-481): 1.63e-16: 81.5: 33.33		SF3A2_HUMAN (710-832): 4.5e-14: 77.6: 13.82
+	Mm
		313435 GRAP2_MOUSE (50-194): 1.58e-17: 86.5: 17.24		PTN23_MOUSE (255-823): 1.83e-09: 63.9: 11.09