HitPredict

Interactor 1: HM20A (Q9NP66)
High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1)
Gene: HMG20A

Interactor 2: HM20B (Q9P0W2)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (HMG domain-containing protein 2) (HMG domain-containing protein HMGX2) (Sox-like transcriptional factor) (Structural DNA-binding protein BRAF35)
Gene: HMG20B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 26186194, 28514442, 32296183, 33961781, 26496610, 22570500, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~HMG_box
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006325 - chromatin organization
GO:0010468 - regulation of gene expression
GO:0033234 - negative regulation of protein sumoylation
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 347
Hs

1 317
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Last updated: 11Aug2025