HitPredict

Interactor 1: ITSN2 (Q9NZM3)
Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein)
Gene: ITSN2

Interactor 2: CBLC (Q9ULV8)
E3 ubiquitin-protein ligase CBL-C (EC 2.3.2.27) (RING finger protein 57) (RING-type E3 ubiquitin transferase CBL-C) (SH3-binding protein CBL-3) (SH3-binding protein CBL-C) (Signal transduction protein CBL-C)
Gene: CBLC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1697 Hs			1 474
+	Hs
		1097958 ITSN2_HUMAN (1-1697): 0: 934: 100.00		CBLB_HUMAN (4-471): 0: 704: 41.18
+	Hs
		651445 ITSN2_HUMAN (1-1697): 0: 934: 100.00		CBL_HUMAN (11-473): 0: 695: 42.14
+	Mm
		1189601 ITSN2_MOUSE (1-1697): 0: 874: 89.86		CBLB_MOUSE (4-471): 0: 707: 41.18
+	Mm
		651588 ITSN2_MOUSE (1-1697): 0: 874: 89.86		CBL_MOUSE (13-473): 0: 695: 43.73
+	Hs
		1097936 ITSN1_HUMAN (2-1693): 0: 828: 56.00		CBLB_HUMAN (4-471): 0: 704: 41.18
+	Hs
		651340 ITSN1_HUMAN (2-1693): 0: 828: 56.00		CBL_HUMAN (11-473): 0: 695: 42.14
+	Mm
		651587 ITSN1_MOUSE (2-1693): 0: 825: 55.96		CBL_MOUSE (13-473): 0: 695: 43.73
+	Hs
		1154195 ITSN1_HUMAN (2-1693): 0: 828: 56.00		CBLC_HUMAN (1-474): 0: 687: 100.00
+	Hs
		651448 EP15R_HUMAN (11-510): 1.51e-36: 152: 16.77		CBL_HUMAN (11-473): 0: 695: 42.14
+	Hs
		1458285 EP15R_HUMAN (11-510): 1.51e-36: 152: 16.77		CBLC_HUMAN (1-474): 0: 687: 100.00
+	Hs
		584532 VAV_HUMAN (255-1041): 6.16e-24: 111: 12.88		CBLB_HUMAN (4-471): 0: 704: 41.18
+	Hs
		584472 VAV_HUMAN (255-1041): 6.16e-24: 111: 12.88		CBL_HUMAN (11-473): 0: 695: 42.14
+	Hs
		1097960 VAV3_HUMAN (255-1038): 3.63e-19: 96.5: 13.46		CBLB_HUMAN (4-471): 0: 704: 41.18
+	Hs
		651446 ARHGC_HUMAN (1189-1535): 2.95e-21: 103: 27.07		CBL_HUMAN (11-473): 0: 695: 42.14
+	Mm
		1189575 EP15R_MOUSE (13-132): 1.87e-16: 87.7: 27.87		CBLB_MOUSE (4-471): 0: 707: 41.18
+	Mm
		86323 VAV2_MOUSE (616-1183): 1.83e-13: 78: 13.13		B9EKI5_MOUSE (4-471): 0: 706: 41.18
+	Mm
		651532 EP15R_MOUSE (13-132): 1.87e-16: 87.7: 27.87		CBL_MOUSE (13-473): 0: 695: 43.73
+	Hs
		913646 VAV2_HUMAN (584-1183): 8.14e-12: 72.6: 11.00		CBLB_HUMAN (4-471): 0: 704: 41.18
+	Hs
		651233 VAV2_HUMAN (584-1183): 8.14e-12: 72.6: 11.00		CBL_HUMAN (11-473): 0: 695: 42.14
+	Dm
		118276 M9ND00_DROME (614-1224): 3.16e-15: 83.7: 13.68		O46034_DROME (9-429): 0: 674: 45.52