HitPredict

Interactor 1: MCCB (Q9V9A7)
Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)
Gene: Mccc2

Interactor 2: Q9V9T5 (Q9V9T5)
GM14617p (Methylcrotonoyl-CoA carboxylase 1, isoform A) (Methylcrotonoyl-CoA carboxylase 1, isoform C)
Gene: Mccc1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Biotin_carb_C~Carboxyl_trans, Biotin_lipoyl~Carboxyl_trans
Common GO terms GO:0004485 - methylcrotonoyl-CoA carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:1905202 - methylcrotonoyl-CoA carboxylase complex
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 578
Dm

1 698
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 11Aug2025