HitPredict

Interactor 1: Q9VJI7 (Q9VJI7)
U6 snRNA-associated Sm-like protein LSm7
Gene: LSm7

Interactor 2: Q9VKW8 (Q9VKW8)
U6 snRNA-associated Sm-like protein LSm4
Gene: CG5356

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.812

Property	Details
Experiments	14605208, 20353594, 38944040
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0000956 - nuclear-transcribed mRNA catabolic process GO:0005688 - U6 snRNP GO:0097526 - spliceosomal tri-snRNP complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 110 Dm			1 154
+	Hs
		1460921 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		LSM4_HUMAN (1-88): 1.04e-40: 134: 88.64
+	Dm
		232184 Q9VJI7_DROME (1-110): 6.02e-39: 127: 100.00		SMD3_DROME (2-105): 1.46e-29: 107: 29.81
+	Ce
		1166986 Q23543_CAEEL (10-110): 8.94e-32: 109: 56.44		LSM4_CAEEL (1-82): 8.39e-36: 122: 76.83
+	Dm
		1478478 Q9VJI7_DROME (1-110): 6.02e-39: 127: 100.00		Q9VTW6_DROME (1-88): 2.17e-29: 104: 35.87
+	Hs
		974864 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		SMD3_HUMAN (2-105): 3.33e-30: 107: 31.73
+	Hs
		974491 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		SMD1_HUMAN (1-90): 1.11e-29: 106: 27.96
+	Hs
		1460917 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		LSM2_HUMAN (1-88): 2.36e-28: 102: 34.78
+	Hs
		974076 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		RUXF_HUMAN (3-70): 7.44e-26: 95.5: 33.82
+	Dm
		1173249 Q9VJI7_DROME (1-110): 6.02e-39: 127: 100.00		RUXF_DROME (3-70): 2.61e-18: 76.2: 32.35
+	Dm
		232170 RSMB_DROME (24-95): 1.98e-24: 93.4: 26.03		SMD3_DROME (2-105): 1.46e-29: 107: 29.81
+	Sc
		795905 LSM7_YEAST (2-101): 2.51e-29: 103: 43.14		LSM2_YEAST (1-87): 2.74e-26: 97: 30.77
+	Sc
		818034 LSM7_YEAST (2-101): 2.51e-29: 103: 43.14		LSM4_YEAST (1-82): 3.63e-25: 96.7: 38.04
+	Hs
		974231 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		SMD3_HUMAN (2-105): 3.33e-30: 107: 31.73
+	Dm
		1052591 RSMB_DROME (24-95): 1.98e-24: 93.4: 26.03		SMD1_DROME (1-90): 8.29e-30: 106: 25.81
+	Hs
		974229 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		SMD1_HUMAN (1-90): 1.11e-29: 106: 27.96
+	Sc
		795885 LSM1_YEAST (3-102): 5.6e-27: 99.2: 25.23		LSM2_YEAST (1-87): 2.74e-26: 97: 30.77
+	Sc
		818014 LSM1_YEAST (3-102): 5.6e-27: 99.2: 25.23		LSM4_YEAST (1-82): 3.63e-25: 96.7: 38.04
+	Hs
		974295 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		LSM2_HUMAN (1-88): 2.36e-28: 102: 34.78
+	Hs
		974263 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		LSM10_HUMAN (3-99): 4.69e-27: 99.7: 25.25
+	Hs
		973870 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		RUXF_HUMAN (3-70): 7.44e-26: 95.5: 33.82