HitPredict

Interactor 1: Q9VJI7 (Q9VJI7)
U6 snRNA-associated Sm-like protein LSm7
Gene: LSm7

Interactor 2: Q9VTW6 (Q9VTW6)
U6 snRNA-associated Sm-like protein LSm2
Gene: DmelCG10418

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005688 - U6 snRNP GO:0071011 - precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome and 1 others more... GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 110 Dm			1 95
+	Dm
		1478475 Q9VJI7_DROME (1-110): 6.02e-39: 127: 100.00		Q9VKW8_DROME (1-95): 3.06e-32: 111: 28.57
+	Hs
		1460917 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		LSM2_HUMAN (1-95): 1.9e-35: 117: 91.58
+	Hs
		1460921 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		LSM4_HUMAN (1-87): 5.86e-30: 105: 31.03
+	Dm
		1173249 Q9VJI7_DROME (1-110): 6.02e-39: 127: 100.00		RUXF_DROME (3-84): 1.06e-23: 87.7: 26.83
+	Dm
		232184 Q9VJI7_DROME (1-110): 6.02e-39: 127: 100.00		SMD3_DROME (2-74): 1.33e-22: 86.9: 24.66
+	Hs
		974491 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		SMD1_HUMAN (1-95): 8.67e-28: 99.2: 28.42
+	Hs
		974295 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		LSM2_HUMAN (1-95): 1.9e-35: 117: 91.58
+	Sc
		795905 LSM7_YEAST (2-101): 2.51e-29: 103: 43.14		LSM2_YEAST (1-95): 1.09e-29: 103: 64.21
+	Ce
		1166986 Q23543_CAEEL (10-110): 8.94e-32: 109: 56.44		LSM4_CAEEL (1-83): 4.42e-26: 95: 28.92
+	Sc
		795885 LSM1_YEAST (3-102): 5.6e-27: 99.2: 25.23		LSM2_YEAST (1-95): 1.09e-29: 103: 64.21
+	Hs
		974864 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		SMD3_HUMAN (2-88): 5.93e-23: 86.9: 21.84
+	Hs
		974076 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		RUXF_HUMAN (3-71): 1.13e-22: 85: 31.43
+	Dm
		1052591 RSMB_DROME (24-95): 1.98e-24: 93.4: 26.03		SMD1_DROME (1-94): 5.29e-28: 99.6: 29.79
+	Sc
		818034 LSM7_YEAST (2-101): 2.51e-29: 103: 43.14		LSM4_YEAST (1-83): 2.09e-23: 89.7: 22.83
+	Hs
		974229 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		SMD1_HUMAN (1-95): 8.67e-28: 99.2: 28.42
+	Sc
		818014 LSM1_YEAST (3-102): 5.6e-27: 99.2: 25.23		LSM4_YEAST (1-83): 2.09e-23: 89.7: 22.83
+	Dm
		232170 RSMB_DROME (24-95): 1.98e-24: 93.4: 26.03		SMD3_DROME (2-74): 1.33e-22: 86.9: 24.66
+	Hs
		974231 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		SMD3_HUMAN (2-88): 5.93e-23: 86.9: 21.84
+	Hs
		973870 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		RUXF_HUMAN (3-71): 1.13e-22: 85: 31.43
+	Hs
		974263 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		LSM10_HUMAN (3-87): 1.41e-21: 83.4: 25.88