HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: ARRC (P36575)
Arrestin-C (Cone arrestin) (C-arrestin) (cArr) (Retinal cone arrestin-3) (X-arrestin)
Gene: ARR3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.620

Property	Details
Experiments	16189514, 21516116
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 388
+	Hs
		150907 DVL2_HUMAN (1-736): 0: 547: 100.00		ARRB1_HUMAN (2-385): 0: 641: 57.18
+	Hs
		150875 DVL2_HUMAN (1-736): 0: 547: 100.00		ARRB2_HUMAN (2-379): 0: 591: 52.10
+	Hs
		150687 DVL1_HUMAN (11-736): 7.51e-163: 488: 57.32		ARRB1_HUMAN (2-385): 0: 641: 57.18
+	Xl
		60759 DVL2_XENLA (11-736): 4.16e-163: 490: 71.95		A5J090_XENLA (2-375): 0: 595: 52.63
+	Dm
		580709 DSH_DROME (9-563): 1.78e-121: 379: 46.29		ARRB_DROME (3-375): 2.02e-172: 488: 35.16
+	Hs
		685901 DLG4_HUMAN (108-707): 2.94e-75: 259: 15.53		ARRB2_HUMAN (2-379): 0: 591: 52.10
+	Hs
		685860 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		ARRB2_HUMAN (2-379): 0: 591: 52.10
+	Ce
		101940 G1K0W3_CAEEL (246-345): 8e-11: 67.6: 30.00		ARRB_CAEEL (2-375): 1.92e-178: 504: 42.65