Interactor 1: KMT2D (O14686)
Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)
Gene: KMT2D

Interactor 2: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 31076518, 24981860
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PHD~RRM_1, N-SET~SET
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032259 - methylation
GO:0042800 - histone H3K4 methyltransferase activity
GO:0140945 - histone H3K4 monomethyltransferase activity
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 5537
Hs

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Last updated: 15 Jul 2024