HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 34315543
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PX
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2027 Hs			1 541
+	Hs
		157751 CTRO_HUMAN (1-2027): 0: 1239: 100.00		MAGI1_HUMAN (2-294): 7.49e-14: 76.9: 15.29
+	Hs
		157485 CTRO_HUMAN (1-2027): 0: 1239: 100.00		MAGI3_HUMAN (19-294): 6.28e-13: 73.8: 17.71
+	Hs
		157278 CTRO_HUMAN (1-2027): 0: 1239: 100.00		ZO1_HUMAN (4-254): 4.46e-12: 71.1: 13.60
+	Mm
		878601 CTRO_MOUSE (1-2027): 0: 1139: 93.68		SHAN3_MOUSE (44-148): 2.58e-21: 100: 36.19
+	Hs
		728612 AKT2_HUMAN (44-407): 3.54e-123: 399: 31.40		SNX27_HUMAN (1-541): 0: 628: 100.00
+	Hs
		1095440 AAPK1_HUMAN (73-610): 1.1e-116: 384: 18.13		SNX27_HUMAN (1-541): 0: 628: 100.00
+	Hs
		1396869 ST38L_HUMAN (74-430): 6.63e-69: 242: 35.79		SNX27_HUMAN (1-541): 0: 628: 100.00
+	Hs
		1144298 STK38_HUMAN (87-430): 1.11e-68: 241: 36.29		SNX27_HUMAN (1-541): 0: 628: 100.00
+	Hs
		1106292 ROCK1_HUMAN (647-1329): 3.96e-39: 162: 13.61		SNX27_HUMAN (1-541): 0: 628: 100.00
+	Rn
		205625 KS6B1_RAT (65-433): 1.29e-128: 416: 31.50		NEB1_RAT (40-375): 2.44e-39: 155: 13.85
+	Rn
		205622 AAPK1_RAT (73-602): 1.48e-116: 383: 18.22		NEB1_RAT (40-375): 2.44e-39: 155: 13.85
+	Rn
		204574 AAPK1_RAT (73-602): 1.48e-116: 383: 18.22		NEB2_RAT (40-314): 1.76e-33: 137: 17.98
+	Ce
		92488 WARTS_CAEEL (8-429): 1.49e-135: 450: 29.92		D3YT29_CAEEL (1-135): 1.69e-11: 69.2: 23.91
+	Hs
		122954 SGK1_HUMAN (59-407): 1.34e-121: 393: 31.37		NHRF2_HUMAN (9-207): 2.41e-25: 108: 21.78
+	Hs
		1448687 LATS2_HUMAN (103-400): 4.89e-58: 222: 39.26		LIN7C_HUMAN (35-136): 1.32e-27: 111: 34.95
+	Hs
		1401118 LATS2_HUMAN (103-400): 4.89e-58: 222: 39.26		MAGI1_HUMAN (2-294): 7.49e-14: 76.9: 15.29
+	Hs
		299797 LATS2_HUMAN (103-400): 4.89e-58: 222: 39.26		MPDZ_HUMAN (35-175): 9.92e-13: 73.3: 14.79
+	Hs
		1058947 LATS2_HUMAN (103-400): 4.89e-58: 222: 39.26		ZO1_HUMAN (4-254): 4.46e-12: 71.1: 13.60
+	Mm
		1000205 ROCK2_MOUSE (863-1552): 4e-36: 152: 11.30		NEB2_MOUSE (40-314): 1.76e-33: 137: 17.98
+	Mm
		1000202 ROCK2_MOUSE (863-1552): 4e-36: 152: 11.30		SHAN3_MOUSE (44-148): 2.58e-21: 100: 36.19