Interactor 1: GEMI2 (O14893)
Gem-associated protein 2 (Gemin-2) (Component of gems 2) (Survival of motor neuron protein-interacting protein 1) (SMN-interacting protein 1)
Gene: GEMIN2

Interactor 2: SMN (Q16637)
Survival motor neuron protein (Component of gems 1) (Gemin-1)
Gene: SMN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 23112048, 26908624, 26092730, 12668731, 10942426, 9323129, 24981860, 33961781, 35271311, 34628513, 19928837, 21900206, 21300694, 32296183, 23221635, 23022347, unassigned1304, 21816274, 11714716
Identification Methods affinity chromatography technology, pull down, biochemical, two hybrid, ion exchange chromatography, cosedimentation in solution, light scattering, molecular sieving, two hybrid prey pooling approach, two hybrid array and 6 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains SIP1~SMN
Common GO terms GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 4 others

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Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 280
Hs

1 294
+ Ce
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024