HitPredict

Interactor 1: IKKB (O14920)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: IKBKB

Interactor 2: NBR1 (Q14596)
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
Gene: NBR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29474632
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PB1~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 756 Hs			1 966
+	Hs
		167548 IKKA_HUMAN (1-742): 2.48e-177: 527: 50.47		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Mm
		956454 IKKA_MOUSE (1-742): 3.39e-172: 514: 50.20		NBR1_MOUSE (1-966): 0: 1731: 82.15
+	Hs
		1056158 TBK1_HUMAN (15-370): 8.86e-97: 317: 26.49		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Hs
		568669 KAPCA_HUMAN (4-283): 2.67e-90: 288: 27.66		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Hs
		262271 ULK1_HUMAN (9-222): 5.77e-30: 129: 34.98		NBR1_HUMAN (1-966): 0: 1811: 100.00