HitPredict

Interactor 1: AP3D1 (O14617)
AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin)
Gene: AP3D1

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1904115 - axon cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1153 Hs			1 758
+	Hs
		529741 AP3B2_HUMAN (41-1152): 0: 633: 12.59		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		225768 AP1G1_HUMAN (17-836): 0: 595: 18.83		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		529568 AP2B1_HUMAN (37-965): 0: 580: 14.83		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		529705 AP1B1_HUMAN (37-965): 0: 578: 15.09		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Rn
		620036 AP2B1_RAT (37-965): 0: 580: 14.83		TAU_RAT (1-758): 3.21e-76: 263: 72.11
+	Rn
		98727 AP2B1_RAT (37-965): 0: 580: 14.83		F1LST4_RAT (1-757): 7.75e-76: 262: 72.21
+	Hs
		530679 COPG1_HUMAN (32-869): 5.95e-174: 536: 12.63		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		530502 COPG2_HUMAN (32-869): 1.5e-172: 532: 12.76		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Mm
		530918 AP2B1_MOUSE (37-965): 0: 579: 14.83		TAU_MOUSE (1-758): 8.57e-72: 250: 70.17
+	Hs
		323658 AP2A2_HUMAN (16-652): 7.07e-149: 472: 19.68		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Hs
		344610 AP2A1_HUMAN (16-729): 3.61e-148: 471: 18.78		TAU_HUMAN (1-758): 6.41e-90: 300: 100.00
+	Rn
		98773 Q66HM2_RAT (16-636): 5.42e-150: 475: 20.15		F1LST4_RAT (1-757): 7.75e-76: 262: 72.21
+	Rn
		614859 AP2A2_RAT (16-701): 1.67e-148: 471: 19.97		TAU_RAT (1-758): 3.21e-76: 263: 72.11
+	Mm
		530700 AP2A1_MOUSE (16-658): 9.22e-150: 475: 20.17		TAU_MOUSE (1-758): 8.57e-72: 250: 70.17
+	Hs
		989161 AP2B1_HUMAN (37-965): 0: 580: 14.83		MAGL2_HUMAN (276-755): 1.31e-17: 90.1: 8.68
+	Hs
		215915 AP2B1_HUMAN (37-965): 0: 580: 14.83		SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41
+	Hs
		215919 AP1B1_HUMAN (37-965): 0: 578: 15.09		SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41
+	Hs
		215887 AP2A2_HUMAN (16-652): 7.07e-149: 472: 19.68		SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41
+	Hs
		215889 AP2A1_HUMAN (16-729): 3.61e-148: 471: 18.78		SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41
+	Rn
		1224312 Q66HM2_RAT (16-636): 5.42e-150: 475: 20.15		SYNJ1_RAT (339-746): 5.7e-10: 65.4: 12.74