HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: NUAK2 (Q9H093)
NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)
Gene: NUAK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	28514442, 33961781, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1030 Hs			1 628
+	Hs
		161260 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		NUAK1_HUMAN (3-628): 2.28e-155: 463: 53.95
+	Hs
		1318219 PP12C_HUMAN (538-1030): 4.93e-33: 139: 20.35		NUAK2_HUMAN (1-628): 0: 592: 100.00
+	Hs
		862065 DAPK1_HUMAN (43-515): 3.48e-54: 208: 15.55		MARK2_HUMAN (6-613): 9.9e-150: 453: 26.75
+	Hs
		647851 DAPK1_HUMAN (43-515): 3.48e-54: 208: 15.55		MARK3_HUMAN (5-625): 3.05e-141: 430: 25.54
+	Hs
		229975 PP12C_HUMAN (538-1030): 4.93e-33: 139: 20.35		NUAK1_HUMAN (3-628): 2.28e-155: 463: 53.95
+	Hs
		225111 MYPT2_HUMAN (1-905): 6.08e-21: 101: 11.37		NUAK1_HUMAN (3-628): 2.28e-155: 463: 53.95