HitPredict

Interactor 1: AZIN1 (O14977)
Antizyme inhibitor 1 (AZI) (AZI1) (Ornithine decarboxylase antizyme inhibitor)
Gene: AZIN1

Interactor 2: OAZ2 (O95190)
Ornithine decarboxylase antizyme 2 (AZ2) (ODC-Az 2)
Gene: OAZ2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.900

Property	Details
Experiments	17353931, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ODC_AZ~Orn_Arg_deC_N, ODC_AZ~Orn_DAP_Arg_deC
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 448 Hs			1 189
+	Hs
		306924 DCOR_HUMAN (1-446): 0: 573: 49.56		OAZ2_HUMAN (1-189): 2.38e-107: 306: 100.00
+	Hs
		516205 DCOR_HUMAN (1-446): 0: 573: 49.56		OAZ1_HUMAN (18-181): 1.36e-89: 263: 58.43
+	Hs
		306928 AZIN2_HUMAN (1-438): 0: 516: 43.85		OAZ2_HUMAN (1-189): 2.38e-107: 306: 100.00
+	Mm
		139601 AZIN2_MOUSE (1-438): 1.31e-172: 493: 42.73		OAZ2_MOUSE (1-189): 2.93e-107: 306: 99.47
+	Hs
		161754 AZIN1_HUMAN (1-448): 0: 535: 100.00		OAZ1_HUMAN (18-181): 1.36e-89: 263: 58.43
+	Hs
		516220 DCOR_HUMAN (1-446): 0: 573: 49.56		OAZ3_HUMAN (28-185): 5.12e-69: 211: 34.59
+	Hs
		870311 AZIN2_HUMAN (1-438): 0: 516: 43.85		OAZ1_HUMAN (18-181): 1.36e-89: 263: 58.43
+	Mm
		870316 AZIN2_MOUSE (1-438): 1.31e-172: 493: 42.73		OAZ1_MOUSE (18-189): 2.02e-93: 273: 55.75
+	Hs
		161763 AZIN1_HUMAN (1-448): 0: 535: 100.00		OAZ3_HUMAN (28-185): 5.12e-69: 211: 34.59
+	Hs
		1283666 AZIN2_HUMAN (1-438): 0: 516: 43.85		OAZ3_HUMAN (28-185): 5.12e-69: 211: 34.59
+	Mm
		1207363 AZIN2_MOUSE (1-438): 1.31e-172: 493: 42.73		OAZ3_MOUSE (31-185): 6.38e-76: 229: 37.58