HitPredict

Interactor 1: HNRDL (O14979)
Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1)
Gene: HNRNPDL

Interactor 2: ROA2 (P22626)
Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)
Gene: HNRNPA2B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	35271311, 30021884, 37071682
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 420 Hs			1 353
+	Hs
		453146 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00
+	Hs
		609770 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00
+	Hs
		162035 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67
+	Hs
		161948 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95
+	Hs
		162045 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		453331 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67
+	Hs
		453107 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95
+	Hs
		516424 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95
+	Hs
		453351 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		852054 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77
+	Hs
		161942 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		ROA1_HUMAN (3-96): 6.48e-16: 79.8: 31.92
+	Hs
		162063 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		RA1L2_HUMAN (3-96): 1.58e-15: 78.2: 31.92
+	Dm
		822820 RB27C_DROME (143-407): 8.49e-78: 248: 29.49		RB87F_DROME (100-199): 6.5e-21: 94.4: 27.00
+	Hs
		453229 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		ROA3_HUMAN (3-103): 2.78e-17: 84: 33.66
+	Hs
		453095 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		ROA1_HUMAN (3-96): 6.48e-16: 79.8: 31.92
+	Hs
		453392 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		RA1L2_HUMAN (3-96): 1.58e-15: 78.2: 31.92
+	Hs
		852075 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		RA1L2_HUMAN (3-96): 1.58e-15: 78.2: 31.92
+	Dm
		432486 RB27C_DROME (143-407): 8.49e-78: 248: 29.49		ROA1_DROME (3-104): 9e-18: 85.1: 25.96