HitPredict

Interactor 1: HNRDL (O14979)
Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1)
Gene: HNRNPDL

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 420 Hs			1 768
+	Hs
		453344 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		852050 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		609851 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		162040 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		162041 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		453345 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		852051 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		609852 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		609853 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		162037 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		453342 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		852048 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		162038 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		609849 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		453343 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		852049 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		609850 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		162106 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		453518 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		852124 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		CUL5_HUMAN (25-768): 0: 597: 23.77