HitPredict

Interactor 1: HNRDL (O14979)
Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1)
Gene: HNRNPDL

Interactor 2: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

Property	Details
Experiments	35271311, 36652389, 30021884, 37071682
Identification Methods	affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006396 - RNA processing and 1 others more... GO:0010468 - regulation of gene expression
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 420 Hs			1 355
+	Hs
		453351 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		852054 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		HNRPD_HUMAN (1-355): 9.1e-72: 229: 100.00
+	Hs
		162127 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		453567 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		ROAA_HUMAN (30-355): 3.41e-55: 185: 53.89
+	Hs
		162035 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52
+	Hs
		161948 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		453229 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		ROA3_HUMAN (64-265): 2.66e-50: 174: 37.02
+	Hs
		161962 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		453331 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PABP4_HUMAN (88-272): 4.65e-43: 159: 18.52
+	Hs
		453107 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		516424 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		PABP1_HUMAN (88-272): 2.1e-42: 157: 16.93
+	Hs
		453146 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		609770 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		ROA2_HUMAN (98-277): 8.38e-39: 142: 41.40
+	Hs
		161942 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		162063 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		RA1L2_HUMAN (46-167): 1.11e-13: 72.9: 27.87
+	Hs
		453095 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		ROA1_HUMAN (63-177): 4.79e-20: 92: 26.83
+	Hs
		453392 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		RA1L2_HUMAN (46-167): 1.11e-13: 72.9: 27.87
+	Hs
		852075 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		RA1L2_HUMAN (46-167): 1.11e-13: 72.9: 27.87