HitPredict

Interactor 1: UB2L6 (O14933)
Ubiquitin/ISG15-conjugating enzyme E2 L6 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L6) (Retinoic acid-induced gene B protein) (RIG-B) (UbcH8) (Ubiquitin carrier protein L6) (Ubiquitin-protein ligase L6)
Gene: UBE2L6

Interactor 2: RN122 (Q9H9V4)
RING finger protein 122
Gene: RNF122

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 153 Hs			1 155
+	Hs
		168577 UB2L6_HUMAN (1-153): 2.21e-98: 281: 100.00		RN150_HUMAN (28-152): 4.49e-26: 103: 22.06
+	Hs
		1294294 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		GOLI_HUMAN (25-154): 1.01e-29: 113: 27.66
+	Hs
		906695 UB2D1_HUMAN (2-149): 1.12e-75: 223: 38.93		GOLI_HUMAN (25-154): 1.01e-29: 113: 27.66
+	Hs
		1461632 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		RN150_HUMAN (28-152): 4.49e-26: 103: 22.06
+	Hs
		1229146 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		RNF43_HUMAN (27-148): 1.32e-24: 100: 23.36
+	Hs
		906677 UB2D1_HUMAN (2-149): 1.12e-75: 223: 38.93		RNF43_HUMAN (27-148): 1.32e-24: 100: 23.36
+	Hs
		906718 UB2D1_HUMAN (2-149): 1.12e-75: 223: 38.93		RN128_HUMAN (33-139): 1.4e-24: 99.4: 21.95
+	Hs
		220521 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		RNF13_HUMAN (34-140): 3.51e-24: 97.9: 23.64
+	Zm
		77732 B4FC97_MAIZE (2-149): 4.48e-76: 224: 36.24		B6U926_MAIZE (87-145): 7.1e-24: 97: 32.20
+	Hs
		220481 UB2D1_HUMAN (2-149): 1.12e-75: 223: 38.93		RNF13_HUMAN (34-140): 3.51e-24: 97.9: 23.64
+	Hs
		1435277 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		RN167_HUMAN (31-137): 1.16e-23: 96.3: 26.79
+	Hs
		1414950 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		RN126_HUMAN (89-149): 1.22e-23: 95.5: 37.71
+	Hs
		1461266 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		AMFR_HUMAN (32-153): 6.24e-23: 95.5: 23.31
+	Hs
		906783 UB2D1_HUMAN (2-149): 1.12e-75: 223: 38.93		RN167_HUMAN (31-137): 1.16e-23: 96.3: 26.79
+	Hs
		906765 UB2D1_HUMAN (2-149): 1.12e-75: 223: 38.93		RN126_HUMAN (89-149): 1.22e-23: 95.5: 37.71
+	Hs
		1359375 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		ZNRF4_HUMAN (18-146): 3.2e-22: 92.9: 21.32
+	Hs
		1490989 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		RN115_HUMAN (83-147): 1.14e-22: 92.8: 35.39
+	Hs
		906721 UB2D1_HUMAN (2-149): 1.12e-75: 223: 38.93		ZNRF4_HUMAN (18-146): 3.2e-22: 92.9: 21.32
+	Hs
		1429974 UB2D4_HUMAN (2-149): 4.15e-76: 224: 38.93		RNF38_HUMAN (93-133): 4.59e-09: 55.8: 51.22
+	Hs
		906780 UB2D1_HUMAN (2-149): 1.12e-75: 223: 38.93		RNF38_HUMAN (93-133): 4.59e-09: 55.8: 51.22