HitPredict

Interactor 1: BET1 (O15155)
BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18)
Gene: BET1

Interactor 2: VAMP7 (P51809)
Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1) (Tetanus-insensitive VAMP) (Ti-VAMP)
Gene: VAMP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29568061, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005789 - endoplasmic reticulum membrane GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport GO:0015031 - protein transport GO:0016020 - membrane and 1 others more... GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 118 Hs			1 220
+	Dm
		1178137 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		Q7JYX5_DROME (1-218): 3.74e-85: 253: 52.29
+	Hs
		169333 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16
+	Hs
		169321 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42
+	Rn
		1125559 BET1_RAT (1-118): 6.04e-46: 145: 93.22		YKT6_RAT (23-179): 1.89e-54: 174: 22.79
+	Mm
		193165 BET1_MOUSE (1-118): 3.41e-45: 143: 92.37		YKT6_MOUSE (23-179): 5.71e-55: 175: 22.79
+	Hs
		263378 BET1L_HUMAN (26-115): 3.07e-22: 85.8: 35.87		SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16
+	Dm
		115845 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		M9PGI6_DROME (24-204): 2.11e-53: 172: 26.23
+	Hs
		235130 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16
+	Dm
		1374918 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		Q9W3M8_DROME (5-179): 4.42e-51: 165: 21.02
+	Hs
		180946 BET1L_HUMAN (26-115): 3.07e-22: 85.8: 35.87		YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42
+	Sc
		611770 BET1_YEAST (13-114): 6.27e-25: 93.5: 22.12		YKT6_YEAST (5-179): 3.71e-52: 168: 22.73
+	Rn
		192329 BET1L_RAT (26-114): 9.01e-22: 84.6: 36.26		YKT6_RAT (23-179): 1.89e-54: 174: 22.79
+	Hs
		180766 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42
+	Sc
		605819 BET1_YEAST (13-114): 6.27e-25: 93.5: 22.12		SEC22_YEAST (37-206): 4.98e-49: 161: 20.93
+	Sc
		611796 BET1_YEAST (13-114): 6.27e-25: 93.5: 22.12		NYV1_YEAST (36-208): 2.42e-36: 129: 20.21
+	Dm
		577258 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		SYB_DROME (99-215): 1.35e-32: 116: 26.50
+	Dm
		577224 Q7JRF1_DROME (9-111): 2.25e-24: 96.2: 20.91		SYB_DROME (99-215): 1.35e-32: 116: 26.50
+	Hs
		169594 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		VAMP8_HUMAN (114-193): 3.49e-13: 65.1: 41.25
+	Rn
		1144365 STX6_RAT (10-97): 1.99e-20: 84.6: 19.32		VAMP8_RAT (118-189): 1.24e-10: 58.2: 41.67
+	Hs
		235129 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		VAMP4_HUMAN (124-193): 2.11e-10: 58.5: 41.43