HitPredict

Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	35530152, 19131971, 17510365, 22682247
Identification Methods	affinity chromatography technology, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015630 - microtubule cytoskeleton
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 862 Hs			1 309
+	Hs
		170628 AXIN1_HUMAN (1-862): 0: 1135: 100.00		PP1A_HUMAN (5-296): 0: 504: 46.51
+	Mm
		193179 AXIN1_MOUSE (1-862): 0: 1069: 86.97		PP2AA_MOUSE (1-309): 0: 528: 99.68
+	Mm
		193178 AXIN1_MOUSE (1-862): 0: 1069: 86.97		PP1A_MOUSE (5-296): 0: 504: 46.84
+	Hs
		915309 AXIN2_HUMAN (11-862): 0: 835: 42.47		PP2AB_HUMAN (1-309): 0: 528: 97.41
+	Mm
		906237 RGS14_MOUSE (45-330): 3.14e-65: 230: 22.76		PP1A_MOUSE (5-296): 0: 504: 46.84
+	Mm
		906648 RGS14_MOUSE (45-330): 3.14e-65: 230: 22.76		PP1B_MOUSE (6-299): 3.71e-179: 499: 44.88