Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: AMER1 (Q5JTC6)
APC membrane recruitment protein 1 (Amer1) (Protein FAM123B) (Wilms tumor gene on the X chromosome protein)
Gene: AMER1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.698

The method score is based on:

Property Details
Experiments 17510365, 26496610, 20128690, 22682247
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008013 - beta-catenin binding
GO:0031398 - positive regulation of protein ubiquitination
GO:0045732 - positive regulation of protein catabolic process
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 862
Hs

1 1135
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024