HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26673895, 32916597
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 964
+	Hs
		323594 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		TRI37_HUMAN (1-964): 0: 1226: 100.00
+	Hs
		173323 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TRIM5_HUMAN (1-459): 4.72e-67: 235: 17.11
+	Hs
		172982 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TRI67_HUMAN (10-367): 1e-58: 218: 16.27
+	Hs
		172754 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TRI26_HUMAN (1-313): 4.54e-60: 216: 17.94
+	Hs
		318143 IPO13_HUMAN (17-1029): 3.81e-133: 429: 16.03		TRI67_HUMAN (10-367): 1e-58: 218: 16.27
+	Hs
		1254919 TNPO1_HUMAN (33-1045): 1.82e-132: 425: 13.84		TRI67_HUMAN (10-367): 1e-58: 218: 16.27
+	Hs
		572270 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		TRI27_HUMAN (1-458): 3.63e-69: 241: 14.78
+	Hs
		164594 TNPO2_HUMAN (33-1045): 7.81e-129: 415: 14.41		TRI67_HUMAN (10-367): 1e-58: 218: 16.27
+	Hs
		220932 XPOT_HUMAN (29-1023): 3.56e-126: 410: 14.85		TRI67_HUMAN (10-367): 1e-58: 218: 16.27
+	Hs
		142702 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		TRI38_HUMAN (1-458): 2.94e-64: 226: 15.03
+	Hs
		1255997 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		TRI67_HUMAN (10-367): 1e-58: 218: 16.27
+	Hs
		1255604 XPO5_HUMAN (26-665): 5.82e-100: 344: 16.12		TRI67_HUMAN (10-367): 1e-58: 218: 16.27
+	Hs
		1134246 IMB1_HUMAN (27-908): 2.9e-90: 311: 11.32		TRI67_HUMAN (10-367): 1e-58: 218: 16.27
+	Hs
		1256275 TNPO3_HUMAN (24-901): 9.97e-89: 307: 14.37		TRI67_HUMAN (10-367): 1e-58: 218: 16.27
+	Hs
		279047 IMB1_HUMAN (27-908): 2.9e-90: 311: 11.32		TRIM3_HUMAN (10-265): 7.05e-50: 191: 21.74
+	Hs
		1255147 XPO6_HUMAN (20-380): 2.56e-64: 239: 16.71		TRI67_HUMAN (10-367): 1e-58: 218: 16.27