Interactor 1: OGT1 (O15294)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)
Gene: OGT

Interactor 2: HCFC1 (P51610)
Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]
Gene: HCFC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.742

The method score is based on:

Property Details
Experiments 27705803, 32994395, 21295698, 12670868, 20200153, 21285374
Identification Methods affinity chromatography technology, pull down, enzymatic study, anti bait coimmunoprecipitation, protease assay, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, protein cleavage, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000123 - histone acetyltransferase complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032991 - protein-containing complex
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1046
Hs

1 2035
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024