HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: PKHG7 (Q6ZR37)
Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7)
Gene: PLEKHG7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 691
+	Hs
		177783 IKKA_HUMAN (1-745): 0: 596: 100.00		VAV_HUMAN (227-684): 7.14e-71: 248: 17.67
+	Hs
		177751 IKKA_HUMAN (1-745): 0: 596: 100.00		TRIO_HUMAN (262-685): 3.71e-42: 167: 13.55
+	Hs
		290329 KS6A4_HUMAN (1-402): 4.76e-70: 246: 19.07		PKHG7_HUMAN (1-691): 1.8e-169: 503: 100.00
+	Hs
		692050 MARK3_HUMAN (3-710): 7.65e-122: 384: 16.34		AKP13_HUMAN (147-690): 6.48e-81: 283: 16.29
+	Hs
		1270489 MARK2_HUMAN (2-718): 8.98e-125: 393: 15.28		ARHG2_HUMAN (82-683): 4.21e-73: 256: 15.88
+	Hs
		692111 MARK3_HUMAN (3-710): 7.65e-122: 384: 16.34		ARHG2_HUMAN (82-683): 4.21e-73: 256: 15.88
+	Hs
		1217546 MRCKA_HUMAN (7-655): 3.14e-113: 378: 19.29		ARHG2_HUMAN (82-683): 4.21e-73: 256: 15.88
+	Hs
		605655 KAPCA_HUMAN (3-316): 9.08e-90: 287: 27.41		AKP13_HUMAN (147-690): 6.48e-81: 283: 16.29
+	Rn
		236529 MRCKA_RAT (7-724): 3.25e-116: 386: 18.63		KALRN_RAT (246-685): 5.86e-45: 176: 12.87
+	Hs
		279148 ULK1_HUMAN (7-221): 7.51e-30: 129: 34.50		AKP13_HUMAN (147-690): 6.48e-81: 283: 16.29
+	Hs
		1371052 MARK4_HUMAN (13-224): 1.59e-24: 111: 34.56		ARHG2_HUMAN (82-683): 4.21e-73: 256: 15.88