HitPredict

Interactor 1: MOT4 (O15427)
Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3)
Gene: SLC16A3

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 191
+	Hs
		179117 MOT4_HUMAN (1-465): 7.17e-79: 254: 100.00		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		179095 MOT4_HUMAN (1-465): 7.17e-79: 254: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		179098 MOT4_HUMAN (1-465): 7.17e-79: 254: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		179092 MOT4_HUMAN (1-465): 7.17e-79: 254: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		179080 MOT4_HUMAN (1-465): 7.17e-79: 254: 100.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		179090 MOT4_HUMAN (1-465): 7.17e-79: 254: 100.00		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		564460 MOT1_HUMAN (4-464): 1.68e-65: 220: 40.56		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		238240 MOT2_HUMAN (4-456): 2.26e-67: 224: 43.88		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		238227 MOT2_HUMAN (4-456): 2.26e-67: 224: 43.88		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		866927 MOT1_HUMAN (4-464): 1.68e-65: 220: 40.56		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		238224 MOT2_HUMAN (4-456): 2.26e-67: 224: 43.88		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		238228 MOT2_HUMAN (4-456): 2.26e-67: 224: 43.88		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		238225 MOT2_HUMAN (4-456): 2.26e-67: 224: 43.88		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		238220 MOT2_HUMAN (4-456): 2.26e-67: 224: 43.88		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		866917 MOT1_HUMAN (4-464): 1.68e-65: 220: 40.56		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		866920 MOT1_HUMAN (4-464): 1.68e-65: 220: 40.56		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		238218 MOT2_HUMAN (4-456): 2.26e-67: 224: 43.88		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		545283 MOT1_HUMAN (4-464): 1.68e-65: 220: 40.56		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		238223 MOT2_HUMAN (4-456): 2.26e-67: 224: 43.88		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		436222 MOT1_HUMAN (4-464): 1.68e-65: 220: 40.56		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41