HitPredict

Interactor 1: RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)
Gene: POLR1G

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 538
+	Hs
		134803 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		IMA3_HUMAN (1-538): 7e-156: 456: 45.84
+	Hs
		131345 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		IMA4_HUMAN (3-538): 1.73e-150: 443: 45.91
+	Hs
		179585 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		IMA1_HUMAN (3-538): 1.64e-149: 441: 44.36
+	Hs
		853625 NIPBL_HUMAN (160-509): 1.23e-45: 174: 14.00		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		168647 NIPBL_HUMAN (160-509): 1.23e-45: 174: 14.00		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59