Protein: MICA2
[F-actin]-monooxygenase MICAL2 (EC 1.14.13.225) (MICAL C-terminal-like protein) (Mical-cL) (Molecule interacting with CasL protein 2) (MICAL-2)

Gene: MICA2, MICAL2
Organism: Homo sapiens
Interactions: 119
UniProt ID: O94851

Gene Ontology (top 5):
GO:0001947 - heart looping
GO:0003779 - actin binding
GO:0004497 - monooxygenase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

318989

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

2

7

High-throughput

0.628

High

318940

MYC
Myc proto-oncogene protein

1

13

High-throughput

0.618

High

319012

JPH4
Junctophilin-4

3

3

High-throughput

0.604

High

318996

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

3

High-throughput

0.575

High

158069

COPE
Coatomer subunit epsilon

2

1

High-throughput

0.558

High

318950

VGFR1
Vascular endothelial growth factor receptor 1

1

9

Small-scale

0.553

High

318968

COPA
Coatomer subunit alpha

1

7

High-throughput

0.536

High

318991

RHG15
Rho GTPase-activating protein 15

1

7

High-throughput

0.536

High

319013

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

318942

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.515

High

318949

GFAP
Glial fibrillary acidic protein

1

10

High-throughput

0.515

High

318953

NOS3
Nitric oxide synthase 3

1

4

High-throughput

0.515

High

318957

HD
Huntingtin

1

6

High-throughput

0.515

High

318969

ATX3
Ataxin-3

1

3

High-throughput

0.515

High

129935

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.513

High

319035

ATX10
Ataxin-10

1

0

High-throughput

0.493

High

318955

COPB2
Coatomer subunit beta'

1

8

High-throughput

0.489

High

318974

NUCB2
Nucleobindin-2

1

0

High-throughput

0.481

High

318984

RCN1
Reticulocalbin-1

1

0

High-throughput

0.481

High

319004

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.481

High

319020

TRI54
Tripartite motif-containing protein 54

1

20

High-throughput

0.481

High

302721

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

17

High-throughput

0.479

High

318956

BRCA1
Breast cancer type 1 susceptibility protein

1

18

High-throughput

0.479

High

318958

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

13

High-throughput

0.479

High

318966

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

318973

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

318977

KIF23
Kinesin-like protein KIF23

1

20

High-throughput

0.479

High

318983

KIF14
Kinesin-like protein KIF14

1

15

High-throughput

0.479

High

318963

PSN2
Presenilin-2

1

5

High-throughput

0.470

High

319008

JPH3
Junctophilin-3

1

3

High-throughput

0.470

High

296404

STAM2
Signal transducing adapter molecule 2

1

20

High-throughput

0.445

High

318938

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

4

High-throughput

0.445

High

318939

NB5R3
NADH-cytochrome b5 reductase 3

1

5

High-throughput

0.445

High

318944

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

6

High-throughput

0.445

High

318946

BIP
Endoplasmic reticulum chaperone BiP

1

14

High-throughput

0.445

High

318947

CFTR
Cystic fibrosis transmembrane conductance regulator

1

9

High-throughput

0.445

High

318951

CALR
Calreticulin

1

4

High-throughput

0.445

High

318954

BMI1
Polycomb complex protein BMI-1

1

20

High-throughput

0.445

High

318960

KC1A
Casein kinase I isoform alpha

1

1

High-throughput

0.445

High

318970

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

20

High-throughput

0.445

High

318972

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

8

High-throughput

0.445

High

318975

ARF5
ADP-ribosylation factor 5

1

5

High-throughput

0.445

High

318985

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

318990

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.445

High

318997

RYBP
RING1 and YY1-binding protein

1

4

High-throughput

0.445

High

319000

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.445

High

319009

LPAR1
Lysophosphatidic acid receptor 1

1

6

High-throughput

0.445

High

319014

SCYL1
N-terminal kinase-like protein

1

6

High-throughput

0.445

High

319023

RGAP1
Rac GTPase-activating protein 1

1

14

High-throughput

0.445

High

319028

RTN4
Reticulon-4

1

4

High-throughput

0.445

High

217638

TGON2
Trans-Golgi network integral membrane protein 2

1

12

High-throughput

0.437

High

318945

CFAH
Complement factor H

1

5

Small-scale

0.437

High

211703

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

215471

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

318961

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

318978

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

318980

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.426

High

318986

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.426

High

318998

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.426

High

319001

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.426

High

319016

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.426

High

319019

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

319021

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

319030

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.426

High

319031

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.426

High

319033

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.426

High

319039

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

48467

ESYT2
Extended synaptotagmin-2

1

2

High-throughput

0.407

High

104310

F5H6I7
Atlastin GTPase 3

1

3

High-throughput

0.407

High

161117

ABCD4
Lysosomal cobalamin transporter ABCD4

1

1

High-throughput

0.407

High

213545

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

1

High-throughput

0.407

High

275474

RTN2
Reticulon-2

1

3

High-throughput

0.407

High

283165

ERLN1
Erlin-1

1

1

High-throughput

0.407

High

318937

RTN3
Reticulon-3

1

5

High-throughput

0.407

High

318943

ASGR2
Asialoglycoprotein receptor 2

1

10

High-throughput

0.407

High

318952

CALX
Calnexin

1

4

High-throughput

0.407

High

318962

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.407

High

318967

COPB
Coatomer subunit beta

1

2

High-throughput

0.407

High

318993

NCEH1
Neutral cholesterol ester hydrolase 1

1

1

High-throughput

0.407

High

318995

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

2

High-throughput

0.407

High

319003

ATLA2
Atlastin-2

1

3

High-throughput

0.407

High

319005

SCFD1
Sec1 family domain-containing protein 1

1

3

High-throughput

0.407

High

319007

ATLA1
Atlastin-1

1

3

High-throughput

0.407

High

319010

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.407

High

319011

ASTRA
Protein Aster-A

1

1

High-throughput

0.407

High

319017

ERP44
Endoplasmic reticulum resident protein 44

1

6

High-throughput

0.407

High

319018

ESYT1
Extended synaptotagmin-1

1

4

High-throughput

0.407

High

319026

TMX1
Thioredoxin-related transmembrane protein 1

1

7

High-throughput

0.407

High

319032

PSD3
PH and SEC7 domain-containing protein 3

1

2

High-throughput

0.407

High

319034

VAPA
Vesicle-associated membrane protein-associated protein A

1

4

High-throughput

0.407

High

319036

COPG2
Coatomer subunit gamma-2

1

3

High-throughput

0.407

High

319037

DHRS7
Dehydrogenase/reductase SDR family member 7

1

2

High-throughput

0.407

High

319038

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.407

High

319040

COPG1
Coatomer subunit gamma-1

1

3

High-throughput

0.407

High

318965

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.279

Low

319025

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

318988

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.249

Low

50464

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

60278

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.232

Low

318941

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

0

High-throughput

0.232

Low

318948

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.232

Low

318959

COPD
Coatomer subunit delta

1

0

High-throughput

0.232

Low

318964

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.232

Low

318971

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.232

Low

318976

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

318979

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.232

Low

318981

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.232

Low

318982

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.232

Low

318987

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.232

Low

318992

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.232

Low

318994

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.232

Low

318999

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.232

Low

319002

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.232

Low

319006

SSMM1
Serine-rich single-pass membrane protein 1

1

0

High-throughput

0.232

Low

319015

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low

319022

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.232

Low

319024

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.232

Low

319027

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

319029

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025