HitPredict

Interactor 1: MUSK (O15146)
Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)
Gene: MUSK

Interactor 2: STYX (Q8WUJ0)
Serine/threonine/tyrosine-interacting protein (Inactive tyrosine-protein phosphatase STYX) (Phosphoserine/threonine/tyrosine interaction protein)
Gene: STYX

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 869 Hs			1 223
+	Hs
		532091 KIT_HUMAN (19-865): 1.61e-151: 472: 18.79		STYX_HUMAN (1-223): 3.2e-91: 268: 100.00
+	Hs
		777727 VGFR3_HUMAN (2-861): 7.01e-173: 538: 22.36		DUS19_HUMAN (32-187): 3.45e-55: 177: 33.97
+	Hs
		464047 RET_HUMAN (493-869): 1.95e-118: 388: 33.85		DUS26_HUMAN (27-176): 7.86e-57: 180: 30.46
+	Hs
		439800 INSR_HUMAN (569-857): 8.77e-70: 254: 42.22		STYX_HUMAN (1-223): 3.2e-91: 268: 100.00
+	Hs
		465586 IGF1R_HUMAN (569-852): 1.94e-69: 253: 42.96		STYX_HUMAN (1-223): 3.2e-91: 268: 100.00
+	Hs
		572947 INSRR_HUMAN (569-852): 5.59e-67: 245: 42.61		STYX_HUMAN (1-223): 3.2e-91: 268: 100.00
+	Hs
		326647 INSR_HUMAN (569-857): 8.77e-70: 254: 42.22		DUS14_HUMAN (7-185): 1.9e-63: 197: 31.84
+	Hs
		326648 IGF1R_HUMAN (569-852): 1.94e-69: 253: 42.96		DUS14_HUMAN (7-185): 1.9e-63: 197: 31.84
+	Hs
		439804 INSR_HUMAN (569-857): 8.77e-70: 254: 42.22		SSH1_HUMAN (10-201): 3.16e-56: 194: 28.13
+	Hs
		465590 IGF1R_HUMAN (569-852): 1.94e-69: 253: 42.96		SSH1_HUMAN (10-201): 3.16e-56: 194: 28.13
+	Hs
		326658 FGFR2_HUMAN (21-329): 8.5e-69: 246: 20.05		DUS14_HUMAN (7-185): 1.9e-63: 197: 31.84
+	Hs
		465644 IGF1R_HUMAN (569-852): 1.94e-69: 253: 42.96		DUS15_HUMAN (32-198): 2.97e-58: 187: 33.53
+	Hs
		439793 INSR_HUMAN (569-857): 8.77e-70: 254: 42.22		DUS18_HUMAN (10-185): 1.36e-58: 184: 26.71
+	Hs
		465580 IGF1R_HUMAN (569-852): 1.94e-69: 253: 42.96		DUS18_HUMAN (10-185): 1.36e-58: 184: 26.71
+	Hs
		465549 IGF1R_HUMAN (569-852): 1.94e-69: 253: 42.96		DUS29_HUMAN (22-174): 1.12e-56: 180: 30.77
+	Hs
		465634 IGF1R_HUMAN (569-852): 1.94e-69: 253: 42.96		DUS26_HUMAN (27-176): 7.86e-57: 180: 30.46
+	Hs
		439798 INSR_HUMAN (569-857): 8.77e-70: 254: 42.22		DUS19_HUMAN (32-187): 3.45e-55: 177: 33.97
+	Hs
		465585 IGF1R_HUMAN (569-852): 1.94e-69: 253: 42.96		DUS19_HUMAN (32-187): 3.45e-55: 177: 33.97
+	Hs
		465649 IGF1R_HUMAN (569-852): 1.94e-69: 253: 42.96		DUS21_HUMAN (19-185): 3.02e-55: 176: 26.95
+	Hs
		326700 PTK7_HUMAN (29-289): 2.38e-37: 153: 20.79		DUS14_HUMAN (7-185): 1.9e-63: 197: 31.84