Interactor 1: AXIN1 (O35625)
Axin-1 (Axis inhibition protein 1) (Protein Fused)
Gene: AXIN1

Interactor 2: MP2K1 (P31938)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: Map2k1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 12223491, 18316368
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RGS
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005938 - cell cortex
GO:0010629 - negative regulation of gene expression
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 863
Mm

1 393
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024